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http://hdl.handle.net/1843/61286| Type: | Artigo de Periódico |
| Title: | Abnormalities of cardiac situs and heart disease diagnosed by echocardiography in patients with biliary atresia |
| Authors: | Henrique de Assis Fonseca Tonelli Zilda Maria Alves Meira Sandra Regina Tolentino Castilho Adriana Furletti Machado Guimarães Tháis Costa Nascentes Queiroz Alexandre Rodrigues Ferreira |
| Abstract: | Background: Left isomerism (LI) is a common finding in patients with biliary atresia (BA), and it can be identified by echocardiography. Several comorbidities may be present in patients with LI, including heart disease. Objective: To investigate the prevalence of LI and heart disease in children (< 18 years of age) with BA followed-up at Hospital das Clínicas, UFMG. Methods: This is a cross-sectional study involving patients diagnosed with BA between February 2016 and April 2020 who underwent transthoracic echocardiography and, in case of situs abnormalities, also electrocardiography. Results: Our study recruited 58 patients (mean age: 3.08 years; female/male ratio: 1.5:1). The general prevalence of situs abnormalities was 8.6% (5/58) and the most common one was LI (4/5 or 80%). One patient had situs inversus. Among patients with situs abnormalities, the general prevalence of heart disease was 80% (4/5), apart from anomalies of the inferior vena cava), with pulmonary valve stenosis (PVS) as the only change seen (75% of mild forms and 25% of moderate forms). Among patients with situs abnormalities, the prevalence of rhythm changes was 80% (4/5), and low atrial rhythm was the most common finding (3/4 or 75%). Conclusion: The prevalence of situs abnormalities in our sample was similar to that described in the literature. We observed an exclusive prevalence of PVS and a high prevalence of rhythm changes among patients with LI. Although the diagnosis of isomerism does not initially add much cardiovascular risk to the sample, possible late deterioration should be considered. |
| Subject: | Cardiopatias Atresia biliar |
| language: | eng |
| metadata.dc.publisher.country: | Brasil |
| Publisher: | Universidade Federal de Minas Gerais |
| Publisher Initials: | UFMG |
| metadata.dc.publisher.department: | MED - DEPARTAMENTO DE PEDIATRIA |
| Rights: | Acesso Aberto |
| metadata.dc.identifier.doi: | https://doi.org/10.36660/ijcs.20210207 |
| URI: | http://hdl.handle.net/1843/61286 |
| Issue Date: | Feb-2022 |
| metadata.dc.url.externa: | https://ijcscardiol.org/article/abnormalities-of-cardiac-situs-and-heart-disease-diagnosed-by-echocardiography-in-patients-with-biliary-atresia/ |
| metadata.dc.relation.ispartof: | International Journal of Cardiovascular Sciences (online) |
| Appears in Collections: | Artigo de Periódico |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Abnormalities of cardiac situs and heart disease diagnosed by echocardiography in patients with biliary atresia.pdf | 298.37 kB | Adobe PDF | View/Open |
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