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http://hdl.handle.net/1843/62063| Type: | Artigo de Periódico |
| Title: | Oral lesions containing amyloid-like material |
| Authors: | Carla Isabelly Rodrigues-Fernandes Ricardo Santiago Gomez Oslei Paes de Almeida Pablo Agustin Vargas Ömer Günhan Ramiro Alejandro Tomasi Faizan Alawi Hélder Antônio Rebelo Pontes Felipe Paiva Fonseca Cinthia Bardález López de Cáceres Maria Sissa Pereira Sant'ana Ciro Dantas Soares Maria Goretti Freire de Carvalho Willie van Heerden Liam Robinson Raghu Radhakrishnan Keith Hunter |
| Abstract: | During oral pathology daily practice, true amyloid may be identified in oral amyloidosis and several odontogenic tumors. However, histologic examination often reveals other oral and perioral diseases with similar eosinophilic, acellular, amorphous substances. These include extensive areas of collagenous sclerosis, fibrin deposition, elastic fiber degeneration, and dentinoid material, which may resemble amyloid under light microscopic examination. These materials are often termed "amyloid-like" due to their close histologic resemblance to true amyloid. The rarity of most of these conditions and their strong histologic similarity may hamper an accurate diagnosis. Definitive diagnosis of these lesions may require clinical correlation; laboratory evaluation; histochemical or immunohistochemical reactions; and, in some cases, genetic investigation. In this review, we describe the main clinicopathologic features of this group of diseases that may manifest in the oral and/or perioral regions and that have in common the presence of amyloid-like material deposition. |
| Subject: | Amyloid Pathology, oral Medical examination Diagnosis Genetics |
| language: | eng |
| metadata.dc.publisher.country: | Brasil |
| Publisher: | Universidade Federal de Minas Gerais |
| Publisher Initials: | UFMG |
| metadata.dc.publisher.department: | FAO - DEPARTAMENTO DE CLÍNICA |
| Rights: | Acesso Restrito |
| metadata.dc.identifier.doi: | https://doi.org/10.1016/j.oooo.2021.01.016 |
| URI: | http://hdl.handle.net/1843/62063 |
| Issue Date: | 2021 |
| metadata.dc.url.externa: | https://www.sciencedirect.com/science/article/pii/S2212440321000444?via%3Dihub |
| metadata.dc.relation.ispartof: | Oral surgery, oral medicine, oral pathology and oral radiology |
| Appears in Collections: | Artigo de Periódico |
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