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Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/62547
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dc.creatorBárbara Proença Nardiassispt_BR
dc.creatorSandra Lyonpt_BR
dc.creatorMaria Aparecida de Faria Grossipt_BR
dc.creatorManoel Otávio da Costa Rochapt_BR
dc.date.accessioned2024-01-10T20:10:32Z-
dc.date.available2024-01-10T20:10:32Z-
dc.date.issued2019-
dc.citation.volume61pt_BR
dc.citation.issuee13pt_BR
dc.citation.spage1pt_BR
dc.citation.epage9pt_BR
dc.identifier.doi10.1590/s1678-9946201961013pt_BR
dc.identifier.issn16789946pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/62547-
dc.description.resumoThe present study sought to investigate the risk factors for physical disability upon release from multidrug therapy (MDT) in new cases of leprosy, registered at a referral center in Brazil. This is a longitudinal and retrospective study that evaluated 260 patients. Multivariate analyses, using both the ordinal logistic regression, as well as the classification and regression tree (CART) algorithm were performed to determine the factors associated with physical disability upon release from treatment. The prevalence of disability did not differ significantly between diagnosis and release from treatment. Number of affected nerves and sensory impairment upon diagnosis were risk factors for disability at the end of MDT. The analysis using the CART algorithm resulted in the development of a clinical score to predict the risk of disability upon release from MDT. The decision tree may have a direct applicability in clinical practice for professionals dealing with leprosy, as it allows them to identify patients with a higher risk of physical disability through the use of simple and widely available clinical tests. This study also shows that the disability grade upon admission is the main risk factor for disability upon release from MDT. This result draws attention to the importance of early diagnosis in disability prevention.pt_BR
dc.format.mimetypepdfpt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentMED - DEPARTAMENTO DE CLÍNICA MÉDICApt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofRevista do Instituto de Medicina Tropical de São Paulo-
dc.rightsAcesso Abertopt_BR
dc.subjectLeprosypt_BR
dc.subjectRisk factors.pt_BR
dc.subject.otherLeprosypt_BR
dc.subject.otherRisk factors.pt_BR
dc.titleRisk factors for physical disability upon release from multidrug therapy in new cases of leprosy at a referral center in brazilpt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://doi.org/10.1590/S1678-9946201961013pt_BR
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