Please use this identifier to cite or link to this item:
http://hdl.handle.net/1843/62547| Type: | Artigo de Periódico |
| Title: | Risk factors for physical disability upon release from multidrug therapy in new cases of leprosy at a referral center in brazil |
| Authors: | Bárbara Proença Nardiassis Sandra Lyon Maria Aparecida de Faria Grossi Manoel Otávio da Costa Rocha |
| Abstract: | The present study sought to investigate the risk factors for physical disability upon release from multidrug therapy (MDT) in new cases of leprosy, registered at a referral center in Brazil. This is a longitudinal and retrospective study that evaluated 260 patients. Multivariate analyses, using both the ordinal logistic regression, as well as the classification and regression tree (CART) algorithm were performed to determine the factors associated with physical disability upon release from treatment. The prevalence of disability did not differ significantly between diagnosis and release from treatment. Number of affected nerves and sensory impairment upon diagnosis were risk factors for disability at the end of MDT. The analysis using the CART algorithm resulted in the development of a clinical score to predict the risk of disability upon release from MDT. The decision tree may have a direct applicability in clinical practice for professionals dealing with leprosy, as it allows them to identify patients with a higher risk of physical disability through the use of simple and widely available clinical tests. This study also shows that the disability grade upon admission is the main risk factor for disability upon release from MDT. This result draws attention to the importance of early diagnosis in disability prevention. |
| Subject: | Leprosy Risk factors. |
| language: | eng |
| metadata.dc.publisher.country: | Brasil |
| Publisher: | Universidade Federal de Minas Gerais |
| Publisher Initials: | UFMG |
| metadata.dc.publisher.department: | MED - DEPARTAMENTO DE CLÍNICA MÉDICA |
| Rights: | Acesso Aberto |
| metadata.dc.identifier.doi: | 10.1590/s1678-9946201961013 |
| URI: | http://hdl.handle.net/1843/62547 |
| Issue Date: | 2019 |
| metadata.dc.url.externa: | https://doi.org/10.1590/S1678-9946201961013 |
| metadata.dc.relation.ispartof: | Revista do Instituto de Medicina Tropical de São Paulo |
| Appears in Collections: | Artigo de Periódico |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Risk factors for physical disability upon release from pdfa.pdf | 13.41 MB | Adobe PDF | View/Open |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.