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Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/63156
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dc.creatorAndrea Saade Daher Borjailipt_BR
dc.creatorDanilo Nagib Salomão Paulopt_BR
dc.creatorTarcizo Afonso Nunespt_BR
dc.creatorGiseli Celestino Nunespt_BR
dc.creatorJulia Belizário Silveirapt_BR
dc.creatorFlávia Heiderich Dall'ortopt_BR
dc.creatorGabriel Souza Lorenzonipt_BR
dc.creatorMatheus Eduardo Daher Borjailipt_BR
dc.creatorBianca Prandi Campagnaropt_BR
dc.creatorMaressa Cristiane Malini de Limapt_BR
dc.creatorMarcela Souza Lima Paulopt_BR
dc.date.accessioned2024-01-19T18:44:23Z-
dc.date.available2024-01-19T18:44:23Z-
dc.date.issued2020-
dc.citation.volume35pt_BR
dc.citation.issue1pt_BR
dc.citation.spage7pt_BR
dc.identifier.doihttps://doi.org/10.1590/s0102-865020200100000003pt_BR
dc.identifier.issn01028650pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/63156-
dc.description.resumoPurpose: Comparing survival rates of rats subjected to spleen procedures after fecal peritonitis induction. Assessing changes in TCD4 and CD8 lymphocyte rates before and after the procedures. Correlating animal survival with CD4 and CD8 lymphocytes. Methods: Thirty male Wistar rats were distributed into 3 groups of ten: spleen manipulation (SM); total splenectomy (TS); subtotal splenectomy with preservation of the inferior pole (IP). Rats were subjected to surgical procedure depending on the group. Seven days after surgery they underwent induction of peritonitis and survival time was recorded. All animals were subjected to two blood collections: before surgery and 70 days after it for TCD4/TCD8 lymphocyte counting. Results: Mean survival time was longer in the IP and SM groups and shorter in the TS group; there was significant difference between them. The comparison of the median number of CD4 did not present changes, whereas the comparison of the median number of CD8 decreased in the SM and IP groups. The correlation between the median number of TCD4 and TCD8 lymphocytes and the animals’ survival was not significant. Conclusion: The maintenance of splenic tissue contributed to increase the survival of rats and there was a change in the number of TCD8 lymphocytespt_BR
dc.format.mimetypepdfpt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentMED - DEPARTAMENTO DE CIRURGIApt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofActa Cirúrgica Brasileira-
dc.rightsAcesso Abertopt_BR
dc.subjectSplenectomypt_BR
dc.subjectSpleenpt_BR
dc.subjectPeritonitispt_BR
dc.subjectImmunophenotypingpt_BR
dc.subjectSurvival Ratept_BR
dc.subjectRatspt_BR
dc.subject.otherSplenectomypt_BR
dc.subject.otherPeritonitispt_BR
dc.subject.otherSpleenpt_BR
dc.subject.otherImmunophenotypingpt_BR
dc.subject.otherSurvival Ratept_BR
dc.subject.otherRatspt_BR
dc.titleThe influence of splenic tissue on the survival and tcd4 and tcd8 lymphocyte rates in rats subjected to fecal peritonitis inductionpt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://doi.org/10.1590/s0102-865020200100000003pt_BR
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