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http://hdl.handle.net/1843/63206| Tipo: | Artigo de Periódico |
| Título: | Intravascular and intraparenchymatous hepatic segmentary sclerosis |
| Autor(es): | Guilherme Velloso Diniz Andy Petroianu |
| Resumo: | Purpose: To evaluate the morphological effects of injected sclerosing agents into the liver. Methods: This study was performed on twenty dogs, distributed into five groups: Group 1 (n = 5) - control, Group 2 (n = 5) - injection of 50% glucose solution inside hepatic parenchyma and animals followed during seven days, Group 3 (n = 10) - injection of ethanol inside hepatic parenchyma and animals distribution into two subgroups Subgroup 3A (n = 5) - followed during 24 hours and subgroup 3B (n = 5) - followed during seven days (group 3B), Group 4 (n = 5) - ethanol injection inside left portal vein branch and followed during 24 hours. Livers were macroscopically evaluated, submitted to hepatic arteriography and portography, then histology. Results: All animals in Group 4 died within 23 hours due to diffuse hepatic necrosis. The animals of groups 2 and 3 had a satisfactory evolution. Fibrosis formed in the segment reached by the sclerosant solution and interruption of the contrast flow injected into the portal system. Conclusion: Intrahepatic parenchymal ethanol injection is well tolerated and causes sclerosis restricted to a specific segment; however, intraportal ethanol injection causes massive hepatic necrosis and can lead to death. |
| Assunto: | Liver Necrosis Glucose Hepatectomy Sclerosis Dogs |
| Idioma: | eng |
| País: | Brasil |
| Editor: | Universidade Federal de Minas Gerais |
| Sigla da Instituição: | UFMG |
| Departamento: | MED - DEPARTAMENTO DE CIRURGIA |
| Tipo de Acesso: | Acesso Aberto |
| Identificador DOI: | 10.1590/s0102-865020180090000006 |
| URI: | http://hdl.handle.net/1843/63206 |
| Data do documento: | 2018 |
| metadata.dc.url.externa: | https://doi.org/10.1590/s0102-865020180090000006 |
| metadata.dc.relation.ispartof: | Acta Cirúrgica Brasileira |
| Aparece nas coleções: | Artigo de Periódico |
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| Arquivo | Descrição | Tamanho | Formato | |
|---|---|---|---|---|
| Intravascular and intraparenchymatous hepatic pdfa.pdf | 3.76 MB | Adobe PDF | Visualizar/Abrir |
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