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http://hdl.handle.net/1843/63206| Type: | Artigo de Periódico |
| Title: | Intravascular and intraparenchymatous hepatic segmentary sclerosis |
| Authors: | Guilherme Velloso Diniz Andy Petroianu |
| Abstract: | Purpose: To evaluate the morphological effects of injected sclerosing agents into the liver. Methods: This study was performed on twenty dogs, distributed into five groups: Group 1 (n = 5) - control, Group 2 (n = 5) - injection of 50% glucose solution inside hepatic parenchyma and animals followed during seven days, Group 3 (n = 10) - injection of ethanol inside hepatic parenchyma and animals distribution into two subgroups Subgroup 3A (n = 5) - followed during 24 hours and subgroup 3B (n = 5) - followed during seven days (group 3B), Group 4 (n = 5) - ethanol injection inside left portal vein branch and followed during 24 hours. Livers were macroscopically evaluated, submitted to hepatic arteriography and portography, then histology. Results: All animals in Group 4 died within 23 hours due to diffuse hepatic necrosis. The animals of groups 2 and 3 had a satisfactory evolution. Fibrosis formed in the segment reached by the sclerosant solution and interruption of the contrast flow injected into the portal system. Conclusion: Intrahepatic parenchymal ethanol injection is well tolerated and causes sclerosis restricted to a specific segment; however, intraportal ethanol injection causes massive hepatic necrosis and can lead to death. |
| Subject: | Liver Necrosis Glucose Hepatectomy Sclerosis Dogs |
| language: | eng |
| metadata.dc.publisher.country: | Brasil |
| Publisher: | Universidade Federal de Minas Gerais |
| Publisher Initials: | UFMG |
| metadata.dc.publisher.department: | MED - DEPARTAMENTO DE CIRURGIA |
| Rights: | Acesso Aberto |
| metadata.dc.identifier.doi: | 10.1590/s0102-865020180090000006 |
| URI: | http://hdl.handle.net/1843/63206 |
| Issue Date: | 2018 |
| metadata.dc.url.externa: | https://doi.org/10.1590/s0102-865020180090000006 |
| metadata.dc.relation.ispartof: | Acta Cirúrgica Brasileira |
| Appears in Collections: | Artigo de Periódico |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Intravascular and intraparenchymatous hepatic pdfa.pdf | 3.76 MB | Adobe PDF | View/Open |
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