Please use this identifier to cite or link to this item:
http://hdl.handle.net/1843/63703| Type: | Artigo de Periódico |
| Title: | Epigenetic alterations in ameloblastomas: a literature review |
| Authors: | Erison-Santana Santos Carla-Isabelly Rodrigues-Fernandes Joab-Cabral Cabral Felipe Paiva Fonseca Adriana-Franco-Paes Leme |
| Abstract: | Background Ameloblastoma is a locally aggressive tumor, originated from odontogenic epithelium, and affects the jawbones with an elevated recurrence rate. The molecular mechanisms involved with the pathogenesis of this tumor remain undetermined. This review aimed to describe the current data regarding epigenetic alterations in ameloblastoma. Material and Methods A systematized electronic search was performed in the English-language literature in three databases, combining the following keywords: ameloblastoma, epigenetic, methylation, noncoding RNA, histone acetylation. Results According to the gathered results of 11 studies in this review, epigenetic alterations could induce the development and progression of ameloblastoma. DNA methylation has been the most assessed mechanism in ameloblastomas. Conclusions Current literature data indicate that epigenetic events can be involved in the etiopathogenesis of ameloblastomas. |
| Subject: | Ameloblastoma Epigenomics Methylation RNA, untranslated Enzymes Acetylation |
| language: | eng |
| metadata.dc.publisher.country: | Brasil |
| Publisher: | Universidade Federal de Minas Gerais |
| Publisher Initials: | UFMG |
| metadata.dc.publisher.department: | FAO - DEPARTAMENTO DE CLÍNICA |
| Rights: | Acesso Aberto |
| metadata.dc.identifier.doi: | https://doi.org/10.4317%2Fjced.56191 |
| URI: | http://hdl.handle.net/1843/63703 |
| Issue Date: | 1-Mar-2021 |
| metadata.dc.url.externa: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7920560/ |
| metadata.dc.relation.ispartof: | Journal of Clinical and experimental dentistry |
| Appears in Collections: | Artigo de Periódico |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Epigenetic alterations in ameloblastomas a literature review.pdf | 1.57 MB | Adobe PDF | View/Open |
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