Please use this identifier to cite or link to this item:
http://hdl.handle.net/1843/65652| Type: | Artigo de Periódico |
| Title: | Sharp DNA denaturation in a helicoidal mesoscopic model |
| Authors: | Mateus Rodrigues Leal Gerald Weber |
| Abstract: | The Peyrard-Bishop DNA model describes the molecular interactions with simple potentials which allow efficient calculations of melting temperatures. However, it is based on a Hamiltonian that does not consider the helical twist or any other relevant molecular dimensions. Here, we start from a more realistic 3D model and work out several approximations to arrive at a new non-linear 1D Hamiltonian with a twist angle dependence. Our approximations were numerically compared to full 3D calculations, and established its validity in the regime of small angles. For long DNA sequences we obtain sharp, first-order-like melting, transitions. |
| Subject: | DNA |
| language: | eng |
| metadata.dc.publisher.country: | Brasil |
| Publisher: | Universidade Federal de Minas Gerais |
| Publisher Initials: | UFMG |
| metadata.dc.publisher.department: | ICX - DEPARTAMENTO DE FÍSICA |
| Rights: | Acesso Aberto |
| metadata.dc.identifier.doi: | https://doi.org/10.1016/j.cplett.2020.137781 |
| URI: | http://hdl.handle.net/1843/65652 |
| Issue Date: | 2020 |
| metadata.dc.url.externa: | https://www.sciencedirect.com/science/article/pii/S0009261420306965?via%3Dihub |
| metadata.dc.relation.ispartof: | Chemical Physics Letters |
| Appears in Collections: | Artigo de Periódico |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Sharp DNA denaturation in a helicoidal mesoscopic model.pdf | 1.29 MB | Adobe PDF | View/Open |
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