Use este identificador para citar ou linkar para este item: http://hdl.handle.net/1843/67733
Tipo: Artigo de Periódico
Título: Effectiveness of photobiomodulation therapy in radiation dermatitis: a systematic review and meta-analysis
Autor(es): Beatriz Regina Lima de Aguiar
Eliete Neves Silva Guerra
Ana Gabriela Costa Normando
Carolina de Castro Martins
Paula Elaine Diniz dos Reis
Elaine Barros Ferreira
Resumo: Purpose: To evaluate the effectiveness of photobiomodulation therapy (PBMT) in the prevention and treatment of radiation dermatitis (RD). Methods: A systematic review was conducted using seven databases and the gray literature. We performed a meta-analysis to summarize the effect sizes of response rates (RRs). Results: We included seven clinical trials. Breast cancer patients receiving PBMT developed more grade 1 RD than the control group (RR 1.55, 95 % CI 1.14–2.10, I 2 = 51 %). PBMT appears to prevent RD grade 2 (RR 0.33, 95 % CI 0.09–1.23, I 2 = 85 %) and RD grade 3 (RR 0.21, 95 % CI 0.05–0.94, I 2 = 0%) with very low certainty of evidence. Conclusions: There is very low certainty of evidence that PBMT was effective in the prevention of RD. However, PBMT showed a significant effect to prevent grade 3 RD in breast cancer patients. Thus, further randomized clinical trials are required to confirm the promising effect of PBMT in RD.
Assunto: Radiotherapy
Radiodermatitis
Laser therapy
Low-level light therapy
Meta-analysis
Idioma: eng
País: Brasil
Editor: Universidade Federal de Minas Gerais
Sigla da Instituição: UFMG
Departamento: FAO - DEPARTAMENTO DE ODONTOPEDIATRIA E ORTODONTIA
Tipo de Acesso: Acesso Restrito
Identificador DOI: https://doi.org/10.1016/j.critrevonc.2021.103349
URI: http://hdl.handle.net/1843/67733
Data do documento: Jun-2021
metadata.dc.url.externa: https://www.sciencedirect.com/science/article/pii/S1040842821001372
metadata.dc.relation.ispartof: Critical Reviews in Oncology/Hematology
Aparece nas coleções:Artigo de Periódico

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