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http://hdl.handle.net/1843/67733| Type: | Artigo de Periódico |
| Title: | Effectiveness of photobiomodulation therapy in radiation dermatitis: a systematic review and meta-analysis |
| Authors: | Beatriz Regina Lima de Aguiar Eliete Neves Silva Guerra Ana Gabriela Costa Normando Carolina de Castro Martins Paula Elaine Diniz dos Reis Elaine Barros Ferreira |
| Abstract: | Purpose: To evaluate the effectiveness of photobiomodulation therapy (PBMT) in the prevention and treatment of radiation dermatitis (RD). Methods: A systematic review was conducted using seven databases and the gray literature. We performed a meta-analysis to summarize the effect sizes of response rates (RRs). Results: We included seven clinical trials. Breast cancer patients receiving PBMT developed more grade 1 RD than the control group (RR 1.55, 95 % CI 1.14–2.10, I 2 = 51 %). PBMT appears to prevent RD grade 2 (RR 0.33, 95 % CI 0.09–1.23, I 2 = 85 %) and RD grade 3 (RR 0.21, 95 % CI 0.05–0.94, I 2 = 0%) with very low certainty of evidence. Conclusions: There is very low certainty of evidence that PBMT was effective in the prevention of RD. However, PBMT showed a significant effect to prevent grade 3 RD in breast cancer patients. Thus, further randomized clinical trials are required to confirm the promising effect of PBMT in RD. |
| Subject: | Radiotherapy Radiodermatitis Laser therapy Low-level light therapy Meta-analysis |
| language: | eng |
| metadata.dc.publisher.country: | Brasil |
| Publisher: | Universidade Federal de Minas Gerais |
| Publisher Initials: | UFMG |
| metadata.dc.publisher.department: | FAO - DEPARTAMENTO DE ODONTOPEDIATRIA E ORTODONTIA |
| Rights: | Acesso Restrito |
| metadata.dc.identifier.doi: | https://doi.org/10.1016/j.critrevonc.2021.103349 |
| URI: | http://hdl.handle.net/1843/67733 |
| Issue Date: | Jun-2021 |
| metadata.dc.url.externa: | https://www.sciencedirect.com/science/article/pii/S1040842821001372 |
| metadata.dc.relation.ispartof: | Critical Reviews in Oncology/Hematology |
| Appears in Collections: | Artigo de Periódico |
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