Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/68070
Type: Artigo de Periódico
Title: Indirectness (transferability) is critical when considering existing economic evaluations for GRADE clinical practice guidelines: a systematic review
Authors: John Riva
Meha Bhatt
Carolina de Castro Martins
David Brunarski
Jason Busse
Feng Xie
Holger Schünemann
Jan Brozek
Abstract: Objectives: Grading of Recommendations Assessment, Development and Evaluation (GRADE) practice guideline developers often perform systematic reviews of potential economic evaluations to inform recommendation decision-making. We aimed to identify indirectness characteristics of economic evaluations, related to GRADE evidence-to-decision (EtD) theoretical frameworks, that influence selection of these articles. Study Design and Setting: MEDLINE, EMBASE, CINAHL, and EconLit were systematically searched to May 2020 to identify indirectness characteristics relevant for economic evaluation transferability to GRADE EtD theoretical frameworks. Four reviewers screened citations to identify articles of any type that explored study characteristics most important or relevant to economic evaluation transferability, restricted to English language we generated frequencies of article features, used thematic analysis to summarize study characteristics, and assessed certainty in the evidence using GRADE-CERQual. Results: We included 57 articles, with a dearth of empirical literature—some may have been missed. We identified eight general themes and 28 subthemes most important to transferability from 41% of articles. Moderate-to-high confidence evidence suggested that GRADE EtD domains of population, intervention and comparison research question elements, resource use estimation and methodology, and provider and decision maker acceptability are most important indirectness study characteristics that economists consider when choosing economic evaluation outcomes for use in recommendation decision-making. Conclusion: We have identified factors important for guideline developers to consider when selecting economic evaluations as research evidence. An economic competency on the development team facilitates these endeavors. This supports the GRADE Working Group’s tenant of transparent reporting or availability of sufficient information elsewhere to assess indirectness.
Subject: Cost-benefit analysis
Economics
Health care costs
Evidence-based medicine
Practice guideline
Epidemiologic research design
GRADE Approach
language: eng
metadata.dc.publisher.country: Brasil
Publisher: Universidade Federal de Minas Gerais
Publisher Initials: UFMG
metadata.dc.publisher.department: FAO - DEPARTAMENTO DE ODONTOPEDIATRIA E ORTODONTIA
Rights: Acesso Restrito
metadata.dc.identifier.doi: https://doi.org/10.1016/j.jclinepi.2022.04.011
URI: http://hdl.handle.net/1843/68070
Issue Date: Aug-2022
metadata.dc.url.externa: https://www.sciencedirect.com/science/article/pii/S0895435622000944
metadata.dc.relation.ispartof: Journal of Clinical Epidemiology
Appears in Collections:Artigo de Periódico

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