1. Repositório Institucional da UFMG
2. Publicações Científicas e Culturais
3. Artigo de Periódico

Tipo:	Artigo de Periódico
Título:	Formulations of desensitizing toothpastes for dentin hypersensitivity: a scoping review
Autor(es):	Carolina de Castro Martins John Joseph Riva Ramon Targino Firmino Holger Jens Schünemann
Resumen:	Objective: This study aimed to review evidence from randomized controlled trials (RCTs) to describe: 1) the active ingredients and desensitizing toothpaste brands; 2) the evaluation of these active ingredients over time, and 3) the fluoride and abrasive content in the formulations designed to treat dentin hypersensitivity (DH). Methodology: In total, 138 RCTs and their tested toothpastes were included. Searches were updated up to August 19, 2021. Formulations, reported brands, active ingredients over time, and type of fluoride (ionizable or ionic fluoride) and abrasive (calcium or silica-based) were analyzed (PROSPERO #CRD42018086815). Results: Our trials assessed 368 toothpaste formulations, including 34 placebo (9%), 98 control toothpastes with fluoride (27%), and 236 (64%) with active ingredients to treat DH. We tested the following active ingredients: potassium compounds (n=68, 19%), calcium sodium phosphosilicate (CSP) (n=37, 10%), strontium compounds (n=28, 8%), arginine (n=29, 8%), stannous fluoride (SnF2) (n=21, 6%), hydroxyapatite (n=9, 2%), potassium combined with another active ingredient (n=19, 5%), inorganic salt compounds (n=11, 3%), citrate (n=5, 1%), formaldehyde (n=3, 1%), herbal (n=4, 1%), copolymer (n=1, 0.5%), and trichlorophosphate (TCP) (n=1, 0.5%). The number of toothpaste formulations increased since 1968, with the greatest increment after 2010. Most toothpastes described their type of fluoride as sodium monofluorphosphate (MFP) (n=105, 29%) and NaF (n=82, 22%), with silica-based (n=84, 23%) and calcium-based (n=64, 17%) abrasives. Conclusion: Patients and dentists enjoy an increasing number of brands and active ingredients to decide what desensitizing toothpaste to use. The most common types of fluoride are MFP and NaF.
Asunto:	Systematic review Network meta-analysis Meta-analysis Dentin sensitivity Dentifrices
Idioma:	eng
País:	Brasil
Editor:	Universidade Federal de Minas Gerais
Sigla da Institución:	UFMG
Departamento:	FAO - DEPARTAMENTO DE ODONTOPEDIATRIA E ORTODONTIA
Tipo de acceso:	Acesso Aberto
Identificador DOI:	http://dx.doi.org/10.1590/1678-7757-2021-0410
URI:	http://hdl.handle.net/1843/68088
Fecha del documento:	2022
metadata.dc.url.externa:	https://www.scielo.br/j/jaos/a/nVwXH8tM8M8tbjvcHb4Pkpy/?lang=en
metadata.dc.relation.ispartof:	Journal of Applied Oral Science
Aparece en las colecciones:	Artigo de Periódico

Los elementos en el repositorio están protegidos por copyright, con todos los derechos reservados, salvo cuando es indicado lo contrario.