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Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/68088
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dc.creatorCarolina de Castro Martinspt_BR
dc.creatorJohn Joseph Rivapt_BR
dc.creatorRamon Targino Firminopt_BR
dc.creatorHolger Jens Schünemannpt_BR
dc.date.accessioned2024-05-06T19:11:17Z-
dc.date.available2024-05-06T19:11:17Z-
dc.date.issued2022-
dc.citation.volume30pt_BR
dc.citation.spagee20210410pt_BR
dc.identifier.doihttp://dx.doi.org/10.1590/1678-7757-2021-0410pt_BR
dc.identifier.issn1678-7765pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/68088-
dc.description.resumoObjective: This study aimed to review evidence from randomized controlled trials (RCTs) to describe: 1) the active ingredients and desensitizing toothpaste brands; 2) the evaluation of these active ingredients over time, and 3) the fluoride and abrasive content in the formulations designed to treat dentin hypersensitivity (DH). Methodology: In total, 138 RCTs and their tested toothpastes were included. Searches were updated up to August 19, 2021. Formulations, reported brands, active ingredients over time, and type of fluoride (ionizable or ionic fluoride) and abrasive (calcium or silica-based) were analyzed (PROSPERO #CRD42018086815). Results: Our trials assessed 368 toothpaste formulations, including 34 placebo (9%), 98 control toothpastes with fluoride (27%), and 236 (64%) with active ingredients to treat DH. We tested the following active ingredients: potassium compounds (n=68, 19%), calcium sodium phosphosilicate (CSP) (n=37, 10%), strontium compounds (n=28, 8%), arginine (n=29, 8%), stannous fluoride (SnF2) (n=21, 6%), hydroxyapatite (n=9, 2%), potassium combined with another active ingredient (n=19, 5%), inorganic salt compounds (n=11, 3%), citrate (n=5, 1%), formaldehyde (n=3, 1%), herbal (n=4, 1%), copolymer (n=1, 0.5%), and trichlorophosphate (TCP) (n=1, 0.5%). The number of toothpaste formulations increased since 1968, with the greatest increment after 2010. Most toothpastes described their type of fluoride as sodium monofluorphosphate (MFP) (n=105, 29%) and NaF (n=82, 22%), with silica-based (n=84, 23%) and calcium-based (n=64, 17%) abrasives. Conclusion: Patients and dentists enjoy an increasing number of brands and active ingredients to decide what desensitizing toothpaste to use. The most common types of fluoride are MFP and NaF.pt_BR
dc.description.sponsorshipCAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível Superiorpt_BR
dc.format.mimetypepdfpt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentFAO - DEPARTAMENTO DE ODONTOPEDIATRIA E ORTODONTIApt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofJournal of Applied Oral Science-
dc.rightsAcesso Abertopt_BR
dc.subjectSystematic reviewpt_BR
dc.subjectNetwork meta-analysispt_BR
dc.subjectMeta-analysispt_BR
dc.subjectDentine sensitivitypt_BR
dc.subjectDentifricept_BR
dc.subject.otherSystematic reviewpt_BR
dc.subject.otherNetwork meta-analysispt_BR
dc.subject.otherMeta-analysispt_BR
dc.subject.otherDentin sensitivitypt_BR
dc.subject.otherDentifricespt_BR
dc.titleFormulations of desensitizing toothpastes for dentin hypersensitivity: a scoping reviewpt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://www.scielo.br/j/jaos/a/nVwXH8tM8M8tbjvcHb4Pkpy/?lang=enpt_BR
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