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Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/68726
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dc.creatorMarcelo Pires Nogueira de Carvalhopt_BR
dc.creatorMiriam R. Fernandespt_BR
dc.creatorFábio P. Sellerapt_BR
dc.creatorRalf Lopespt_BR
dc.creatorDaniel F. Montept_BR
dc.creatorAlícia G. Hippólitopt_BR
dc.creatorLiliane Milanelopt_BR
dc.creatorTânia F. Rasopt_BR
dc.creatorNilton Lincopanpt_BR
dc.date.accessioned2024-05-28T14:55:22Z-
dc.date.available2024-05-28T14:55:22Z-
dc.date.issued2020-
dc.citation.volume67pt_BR
dc.citation.issue5pt_BR
dc.citation.spage1804pt_BR
dc.citation.epage1815pt_BR
dc.identifier.doihttps://doi.org/10.1111/tbed.13558pt_BR
dc.identifier.issn1865-1682pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/68726-
dc.description.resumoCTX-M-type extended-spectrum β-lactamase (ESBL)-producing Escherichia coli clones have been increasingly reported worldwide. In this regard, although discussions of transmission routes of these bacteria are in evidence, molecular data are lacking to elucidate the epidemiological impacts of ESBL producers in wild animals. In this study, we have screened 90 wild animals living in a surrounding area of São Paulo, the largest metropolitan city in South America, to monitor the presence of multidrug-resistant (MDR) Gram-negative bacteria. Using a genomic approach, we have analysed eight ceftriaxone-resistant E. coli. Resistome analyses revealed that all E. coli strains carried blaCTX-M-type genes, prevalent in human infections, besides other clinically relevant resistance genes to aminoglycosides, β-lactams, phenicols, tetracyclines, sulphonamides, trimethoprim, fosfomycin and quinolones. Additionally, E. coli strains belonged to international sequence types (STs) ST38, ST58, ST212, ST744, ST1158 and ST1251, and carried several virulence-associated genes. Our findings suggest spread and adaptation of international clones of CTX-M-producing E. coli beyond urban settings, including wildlife from shared environments.pt_BR
dc.description.sponsorshipCNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológicopt_BR
dc.description.sponsorshipFAPEMIG - Fundação de Amparo à Pesquisa do Estado de Minas Geraispt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentVET - DEPARTAMENTO DE CLÍNICA E CIRURGIApt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofTransboundary and Emerging Diseasespt_BR
dc.rightsAcesso Abertopt_BR
dc.subjectEnterobacteralespt_BR
dc.subjectESBLpt_BR
dc.subjectMDR bacteriapt_BR
dc.subjectResistomept_BR
dc.subjectWildlifept_BR
dc.subject.otherEscherichia colipt_BR
dc.subject.otherBactérias Gram-Negativaspt_BR
dc.subject.otherAnimais selvagenspt_BR
dc.titleInternational clones of extended-spectrum β-lactamase (CTX-M)-producing Escherichia coli in peri-urban wild animals, Brazilpt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://onlinelibrary.wiley.com/doi/10.1111/tbed.13558pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-0210-8352pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-4725-0125pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0001-8223-1758pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0003-3787-1988pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0003-0161-5800pt_BR
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