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Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/77063
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dc.creatorRachel Alvarenga Brantpt_BR
dc.creatorFernando Oliveira Costapt_BR
dc.creatorGustavo Henrique de Mattos Pereirapt_BR
dc.creatorRafael Paschoal Esteves Limapt_BR
dc.creatorFernanda Vieira Belémpt_BR
dc.creatorRicardo Santiago Gomezpt_BR
dc.creatorCarolina Castro Martinspt_BR
dc.date.accessioned2024-09-30T22:31:24Z-
dc.date.available2024-09-30T22:31:24Z-
dc.date.issued2023-07-
dc.citation.volume136pt_BR
dc.citation.issue1pt_BR
dc.citation.spagee36pt_BR
dc.citation.epagee37pt_BR
dc.identifier.doihttps://doi.org/10.1016/j.oooo.2023.03.087pt_BR
dc.identifier.issn2212-4411pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/77063-
dc.description.resumoObjective: This systematic review of randomized con trolled trials (RCTs) aimed to assess the effectiveness of treat ments to relieve pain caused by burning mouth syndrome (BMS). Study Design: five databases and grey literature were searched, and the reference lists of included studies were manu ally searched. Independent reviewers selected studies, extracted data, and assessed risk of bias (RoB 2.0). The main outcome was pain relief. For the network meta-analysis (NMA), four compara ble interventions were grouped into different geometries to ensure the transitivity assumption: laser, alpha lipoic acid (ALA), phytotherapics, and anxiolytics/antidepressants. The certainty of evidence was assessed using the GRADE approach for NMA with GRADE minimally contextualized framework. Results: The anxiolytic medicine (clonazepam) likely reduces pain caused by BMS when compared to placebo (MD: -1.97; 95% CI: -2.31; -1.64; moderate certainty). Although laser, ALA, and phytoterapics proved to be better when compared to placebos, the certainty was low or very low. Conclusion: among all tested treatments, only clonaze pan is likely to reduce pain caused by BMS when compared to placebos. Most other treatments had low and very low certainty, mainly due to imprecision and indirectness. More RCTs compar ing treatments against placebo are encouraged to confirm the evidence.pt_BR
dc.description.sponsorshipCAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível Superiorpt_BR
dc.format.mimetypepdfpt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentFAO - DEPARTAMENTO DE CLÍNICApt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofOral Surgery, Oral Medicine, Oral Pathology and Oral Radiologypt_BR
dc.rightsAcesso Restritopt_BR
dc.subject.otherClonazepampt_BR
dc.subject.otherAnti-anxiety agentspt_BR
dc.subject.otherPhytotherapeutic drugspt_BR
dc.subject.otherNetwork meta-analysispt_BR
dc.subject.otherAntidepressive agentspt_BR
dc.subject.otherSystematic reviewpt_BR
dc.titleEfficacy of different treatments for burning mouth syndrome: network meta-analysis using minimally contextualized approapt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://www.sciencedirect.com/science/article/pii/S2212440323001980pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0001-9358-2262pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-7687-1238pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0003-0176-0741pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0003-4343-3845pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0003-1746-2685pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0001-8770-8009pt_BR
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