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http://hdl.handle.net/1843/81285| Type: | Artigo de Periódico |
| Title: | Odontogenic carcinosarcoma: a systematic review |
| Authors: | Lauren Frenzel Schuch José Alcides Almeida de Arruda Leni Verônica de Oliveira Silva Lucas Guimarães Abreu Tarcília Aparecida da Silva Ricardo Alves de Mesquita |
| Abstract: | The aim of this study was to integrate the available data published on odontogenic carcinosarcoma into a comprehensive analysis of their features, treatment and recurrence. An electronic search with no publication date or language restriction was undertaken in March 2018 in the following databases: Medline Ovid, PubMed, Web of Science, Scopus and LILACS. Eligibility criteria included publications having enough clinical, imaginological and histopathological information to confirm a definite diagnosis of the neoplasm. Data were evaluated descriptively and statistically using the MedCalc software. The Kaplan-Meier method was used for survival analysis. The systematic review detected nine articles from eight countries. Six cases with no age predilection occurred in male individuals complaining of painful swelling in the posterior mandible. Radiographically, the lesions were large, with expansive radiolucency and with ill-defined borders and seven cases were associated with preexisting odontogenic lesions. Radical surgery was the treatment of choice in the majority of cases. Recurrences (n = 6), metastasis (n = 4) and death (n = 4) were frequently observed in many cases. Odontogenic carcinosarcoma is a very aggressive neoplasm with a poor prognosis. This study provides knowledge that could help surgeons, oncologists, otorhinolaryngologists and oral maxillofacial pathologists with the diagnosis and management of these lesions. |
| Subject: | Carcinosarcoma Clinical study Head and neck neoplasms Neoplasms Odontogenic tumors Mouth neoplasms Recurrence Surgical oncology Mandible Diagnosis, oral Neoplasm metastasis Death |
| language: | eng |
| metadata.dc.publisher.country: | Brasil |
| Publisher: | Universidade Federal de Minas Gerais |
| Publisher Initials: | UFMG |
| metadata.dc.publisher.department: | FAO - DEPARTAMENTO DE CLÍNICA FAO - DEPARTAMENTO DE ODONTOPEDIATRIA E ORTODONTIA |
| Rights: | Acesso Restrito |
| metadata.dc.identifier.doi: | https://doi.org/10.1016/j.oraloncology.2018.08.017 |
| URI: | http://hdl.handle.net/1843/81285 |
| Issue Date: | Oct-2018 |
| metadata.dc.url.externa: | https://www.sciencedirect.com/science/article/pii/S1368837518303051?via%3Dihub |
| metadata.dc.relation.ispartof: | Oral Oncology |
| Appears in Collections: | Artigo de Periódico |
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