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http://hdl.handle.net/1843/82395| Tipo: | Artigo de Periódico |
| Título: | Sociodemographic and clinical characterization of cases of 1,103 non-syndromic and 66 syndromic odontogenic keratocyst: a brazilian multicenter study |
| Autor(es): | Daiana Cristina Pereira Santana Christany Rodrigues Ferreira Tatiana Nayara Libório-Kimura Lucileide Castro de Oliveira Moreira Jeconias Câmara Caroline Alfaia Silva Elismauro Francisco de Mendonça Nádia do Lago Costa Hélder Antônio Rebelo Pontes Lucas Lacerda de Souza Jurema Freire de Castro Lisboa Larissa Abbehusen Couto Gustavo Pina Godoy Johelle de Santana Passos-Soares Flávia Caló de Aquino Xavier Ricardo Alves de Mesquita Fernanda Aragão Felix Tarcília Aparecida da Silva Cassiano Francisco Weege Nonaka Pollianna Muniz Alves |
| Resumo: | Objectives: This multicenter study aimed to evaluate cases of non-syndrome and syndromic odontogenic keratocyst, as well as cases of recurrence within these two groups. Methods: This descriptive, analytical, retrospective cross-sectional study evaluated the sex, age and presence of multiple lesions in 1,169 individuals seen at 10 Brazilian oral and maxillofacial pathology centers. Of these, 1,341 odontogenic keratocysts were analyzed regarding clinical diagnosis, size, site, imaging appearance, signs and symptoms, type of biopsy, treatment, and recurrence. Results: There was a similar distribution by sex. The median age of non-syndromic and syndromic patients was 32 and 17.5 years, respectively. The posterior mandible was the site most affected by small and large lesions in both groups and in recurrent cases. Unilocular lesions were more frequent, also in recurrent cases. Mainly small lesions showed this imaging appearance. Signs and symptoms were absent in most cases. Conservative treatment was the most frequent modality in all age groups, regardless of the patient's condition and recurrence. Recurrences were uncommon. Conclusion: This study showed a higher frequency of non-syndromic keratocysts in the population. Clinicopathological features related to the involvement of multiple sites, age, and recurrence may differ between syndromic and non-syndromic cases. Furthermore, we found an association between lesion size and some clinical features and between the time interval to recurrence and the syndromic spectrum. Clinical relevance: To contribute to a better understanding of the distribution and association between clinical, imaging, and sociodemographic characteristics in each spectrum of the lesion. |
| Assunto: | Odontogenic cysts Multicenter study Pathology, oral Recurrence Evaluation study Therapeutics |
| Idioma: | eng |
| País: | Brasil |
| Editor: | Universidade Federal de Minas Gerais |
| Sigla da Instituição: | UFMG |
| Departamento: | FAO - DEPARTAMENTO DE CLÍNICA |
| Tipo de Acesso: | Acesso Restrito |
| Identificador DOI: | https://doi.org/10.1007/s00784-023-05313-7 |
| URI: | http://hdl.handle.net/1843/82395 |
| Data do documento: | Nov-2023 |
| metadata.dc.url.externa: | https://link.springer.com/article/10.1007/s00784-023-05313-7 |
| metadata.dc.relation.ispartof: | Clinical oral investigations |
| Aparece nas coleções: | Artigo de Periódico |
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