Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/82395
Type: Artigo de Periódico
Title: Sociodemographic and clinical characterization of cases of 1,103 non-syndromic and 66 syndromic odontogenic keratocyst: a brazilian multicenter study
Authors: Daiana Cristina Pereira Santana
Christany Rodrigues Ferreira
Tatiana Nayara Libório-Kimura
Lucileide Castro de Oliveira Moreira
Jeconias Câmara
Caroline Alfaia Silva
Elismauro Francisco de Mendonça
Nádia do Lago Costa
Hélder Antônio Rebelo Pontes
Lucas Lacerda de Souza
Jurema Freire de Castro Lisboa
Larissa Abbehusen Couto
Gustavo Pina Godoy
Johelle de Santana Passos-Soares
Flávia Caló de Aquino Xavier
Ricardo Alves de Mesquita
Fernanda Aragão Felix
Tarcília Aparecida da Silva
Cassiano Francisco Weege Nonaka
Pollianna Muniz Alves
Abstract: Objectives: This multicenter study aimed to evaluate cases of non-syndrome and syndromic odontogenic keratocyst, as well as cases of recurrence within these two groups. Methods: This descriptive, analytical, retrospective cross-sectional study evaluated the sex, age and presence of multiple lesions in 1,169 individuals seen at 10 Brazilian oral and maxillofacial pathology centers. Of these, 1,341 odontogenic keratocysts were analyzed regarding clinical diagnosis, size, site, imaging appearance, signs and symptoms, type of biopsy, treatment, and recurrence. Results: There was a similar distribution by sex. The median age of non-syndromic and syndromic patients was 32 and 17.5 years, respectively. The posterior mandible was the site most affected by small and large lesions in both groups and in recurrent cases. Unilocular lesions were more frequent, also in recurrent cases. Mainly small lesions showed this imaging appearance. Signs and symptoms were absent in most cases. Conservative treatment was the most frequent modality in all age groups, regardless of the patient's condition and recurrence. Recurrences were uncommon. Conclusion: This study showed a higher frequency of non-syndromic keratocysts in the population. Clinicopathological features related to the involvement of multiple sites, age, and recurrence may differ between syndromic and non-syndromic cases. Furthermore, we found an association between lesion size and some clinical features and between the time interval to recurrence and the syndromic spectrum. Clinical relevance: To contribute to a better understanding of the distribution and association between clinical, imaging, and sociodemographic characteristics in each spectrum of the lesion.
Subject: Odontogenic cysts
Multicenter study
Pathology, oral
Recurrence
Evaluation study
Therapeutics
language: eng
metadata.dc.publisher.country: Brasil
Publisher: Universidade Federal de Minas Gerais
Publisher Initials: UFMG
metadata.dc.publisher.department: FAO - DEPARTAMENTO DE CLÍNICA
Rights: Acesso Restrito
metadata.dc.identifier.doi: https://doi.org/10.1007/s00784-023-05313-7
URI: http://hdl.handle.net/1843/82395
Issue Date: Nov-2023
metadata.dc.url.externa: https://link.springer.com/article/10.1007/s00784-023-05313-7
metadata.dc.relation.ispartof: Clinical oral investigations
Appears in Collections:Artigo de Periódico

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