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http://hdl.handle.net/1843/83321| Tipo: | Artigo de Periódico |
| Título: | Hyaluronic acid accelerates bone repair in human dental sockets: a randomized triple-blind clinical trial |
| Autor(es): | Carlos Eduardo Pinto de Alcântara Maurício Augusto Aquino de Castro Mariana Saturnino de Noronha Paulo Antônio Martins-Junior Renato de Melo Mendes Marcelo Vidigal Caliari Ricardo Alves de Mesquita Anderson José Ferreira |
| Resumo: | This study evaluated the effects of hyaluronic acid (HA) on bone repair of human dental sockets. Thirty-two lower first premolars were extracted from 16 patients (2 per patient) for orthodontic reasons. Following the extractions, one socket was randomly filled with 1% HA gel, while the other was allowed to naturally fill with blood clot. After 30 and 90 days of surgery, patients underwent cone beam computed tomography. Five central orthoradial slices were captured from each socket. The gray intensity was measured in each image and results were reported as mean percentage of bone formation. The buccolingual alveolar ridge width was measured and dimensional changes were compared between the postoperative intervals. The pattern of alveolar trabecular bone was evaluated through the fractal dimension. Treated sockets showed a higher percentage of bone formation and fractal dimension values (58.17% and 1.098, respectively) compared with controls (48.97% and 1.074, respectively) in the 30-day postoperative period (p < 0.05). After 90 days, there was no significant difference between groups. Additionally, no significant difference was found between groups regarding the alveolar dimensions (p > 0.05). Use of 1% HA gel after tooth extraction accelerates bone repair in human dental sockets. |
| Assunto: | Hyaluronic acid Tooth socket Cone-beam computed tomography Osteogenesis Fractals Evaluation study |
| Idioma: | eng |
| País: | Brasil |
| Editor: | Universidade Federal de Minas Gerais |
| Sigla da Instituição: | UFMG |
| Departamento: | FAO - DEPARTAMENTO DE CLÍNICA FAO - DEPARTAMENTO DE ODONTOPEDIATRIA E ORTODONTIA ICB - DEPARTAMENTO DE MORFOLOGIA ICB - DEPARTAMENTO DE PATOLOGIA |
| Tipo de Acesso: | Acesso Aberto |
| Identificador DOI: | https://doi.org/10.1590/1807-3107bor-2018.vol32.0084 |
| URI: | http://hdl.handle.net/1843/83321 |
| Data do documento: | 2018 |
| metadata.dc.url.externa: | https://www.scielo.br/j/bor/a/CRGVc8ksQGW5zdHpCYhHkRB/?lang=en |
| metadata.dc.relation.ispartof: | Brazilian Oral Research |
| Aparece nas coleções: | Artigo de Periódico |
Arquivos associados a este item:
| Arquivo | Descrição | Tamanho | Formato | |
|---|---|---|---|---|
| Hyaluronic acid accelerates bone repair in human dental sockets a randomized triple-blind clinical trial.pdf | 515.33 kB | Adobe PDF | Visualizar/Abrir |
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