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Type:	Artigo de Periódico
Title:	Hyaluronic acid accelerates bone repair in human dental sockets: a randomized triple-blind clinical trial
Authors:	Carlos Eduardo Pinto de Alcântara Maurício Augusto Aquino de Castro Mariana Saturnino de Noronha Paulo Antônio Martins-Junior Renato de Melo Mendes Marcelo Vidigal Caliari Ricardo Alves de Mesquita Anderson José Ferreira
Abstract:	This study evaluated the effects of hyaluronic acid (HA) on bone repair of human dental sockets. Thirty-two lower first premolars were extracted from 16 patients (2 per patient) for orthodontic reasons. Following the extractions, one socket was randomly filled with 1% HA gel, while the other was allowed to naturally fill with blood clot. After 30 and 90 days of surgery, patients underwent cone beam computed tomography. Five central orthoradial slices were captured from each socket. The gray intensity was measured in each image and results were reported as mean percentage of bone formation. The buccolingual alveolar ridge width was measured and dimensional changes were compared between the postoperative intervals. The pattern of alveolar trabecular bone was evaluated through the fractal dimension. Treated sockets showed a higher percentage of bone formation and fractal dimension values (58.17% and 1.098, respectively) compared with controls (48.97% and 1.074, respectively) in the 30-day postoperative period (p < 0.05). After 90 days, there was no significant difference between groups. Additionally, no significant difference was found between groups regarding the alveolar dimensions (p > 0.05). Use of 1% HA gel after tooth extraction accelerates bone repair in human dental sockets.
Subject:	Hyaluronic acid Tooth socket Cone-beam computed tomography Osteogenesis Fractals Evaluation study
language:	eng
metadata.dc.publisher.country:	Brasil
Publisher:	Universidade Federal de Minas Gerais
Publisher Initials:	UFMG
metadata.dc.publisher.department:	FAO - DEPARTAMENTO DE CLÍNICA FAO - DEPARTAMENTO DE ODONTOPEDIATRIA E ORTODONTIA ICB - DEPARTAMENTO DE MORFOLOGIA ICB - DEPARTAMENTO DE PATOLOGIA
Rights:	Acesso Aberto
metadata.dc.identifier.doi:	https://doi.org/10.1590/1807-3107bor-2018.vol32.0084
URI:	http://hdl.handle.net/1843/83321
Issue Date:	2018
metadata.dc.url.externa:	https://www.scielo.br/j/bor/a/CRGVc8ksQGW5zdHpCYhHkRB/?lang=en
metadata.dc.relation.ispartof:	Brazilian Oral Research
Appears in Collections:	Artigo de Periódico

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