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http://hdl.handle.net/1843/83492| Type: | Artigo de Periódico |
| Title: | Pigmented lesions of the oral mucosa: a cross-sectional study of 458 histopathological specimens |
| Authors: | Thalita Soares Tavares Daniela Pereira Meirelles Maria Cássia Ferreira de Aguiar Patrícia Carlos Caldeira |
| Abstract: | Objectives: To evaluate clinical, demographic, and histopathological characteristics of pigmented lesions of the oral mucosa. Materials and methods: A cross-sectional study was conducted over a 64-year period. Information was collected from medical charts, and all archived histopathological specimens with diagnoses of any pigmented lesion were retrieved. Statistical analysis was performed using SPSS software. Results: A total of 34,127 archived specimens were reviewed, revealing 458 (1.34%) pigmented lesions, of which 230 were melanocytic and 228 nonmelanocytic. Most patients were females (74.2%), white-skinned (49.1%), in the third and seventh decades of life (mean of 45 years). Most lesions were macular (59.8%), followed by plaques and nodules (4.8%), measuring 0-5 mm (41.9%). Cheek mucosa (21.0%), alveolar mucosa (16.6%), and gingiva (11.8%) were the most commonly affected sites. Amalgam tattoo was applied in 212 cases (46.3%), followed by melanotic macule (22.9%) and nevus (20.5%). Other diagnoses included racial pigmentation, exogenous pigmentation, melanotic neuroectodermal tumor of infancy, melanoma, melanoacanthoma, smoker's melanosis, and heavy metal pigmentation. Conclusions: Pigmented lesions represent an uncommon diagnosis in oral pathology routines. The most frequent entities are amalgam tattoo, melanotic macule, and nevus. Patients are usually middle-aged women presenting a small, long-lasting, macular lesion on the cheek mucosa. |
| Subject: | Dental amalgam Melanins Mouth mucosa Pigmentation Macular pigment Neuroectodermal tumor, melanotic Nevus, pigmented Diagnosis Melanoma Melanosis Metals, heavy |
| language: | eng |
| metadata.dc.publisher.country: | Brasil |
| Publisher: | Universidade Federal de Minas Gerais |
| Publisher Initials: | UFMG |
| metadata.dc.publisher.department: | FAO - DEPARTAMENTO DE CLÍNICA |
| Rights: | Acesso Restrito |
| metadata.dc.identifier.doi: | https://doi.org/10.1111/odi.12924 |
| URI: | http://hdl.handle.net/1843/83492 |
| Issue Date: | Nov-2018 |
| metadata.dc.url.externa: | https://onlinelibrary.wiley.com/doi/10.1111/odi.12924 |
| metadata.dc.relation.ispartof: | Oral Diseases |
| Appears in Collections: | Artigo de Periódico |
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