Psoríase e cognição: Uma revisão narrativa sobre os impactos da inflamação sistêmica nos processos cognitivos

Abstract

Abstract Psoriasis is a chronic inflammatory skin disease with systemic manifestations that go beyond skin lesions, including potential impacts on cognition. This study reviews the recent scientific literature (2020-2024) to investigate how the systemic inflammation characteristic of the disease can affect specific cognitive functions such as memory, attention and executive functions. The search included articles available in databases such as PubMed and Google Scholar, using specific keywords such as “Psoriasis AND Cognition". Of the 80 articles identified, 29 met the inclusion criteria. The analysis identified evidence that inflammatory and psychological factors, such as depression and anxiety, contribute to cognitive impairment in patients with psoriasis in cognitive performance. Despite this identified evidence, limitations in the studies, with small sample sizes and lack of standardization, make definitive conclusions difficult. This article reinforces the need for more robust studies to better clarify the interaction between psoriasis and cognition and guide therapeutic strategies.