Percepção sensorial tátil perturbada em pacientes oncológicos sob quimioterapia: análise da literatura e validação clínica

Abstract

Cancer patients may develop many chemotherapy toxic effects, including neurosensory toxicity. The disturbed tactile perception (PSTP) is considered a patient's response to anticancer treatment making this phenomenon relevant for the nursing practice. Despite the influence of this problem in patient´s daily activities and quality of life, their representativeness in NANDA-I is still lacking, hampering for nursing care in this population. This is an integrative literature review studyand non-concurrent cohort that aimed validate the diagnosis of nursing diagnoses PSTP in adult cancer patients undergoing chemotherapy. Articles were analyzed and 46 were selected, most (34.8%) cohort studies (LoE III), conducted in the US (32.6%) and published in English (98%). The most relevant related factors (use of neurotoxic chemotherapy, dose accumulation during treatment) and defining characteristics (tingling and numbness, especially on extremities like hands and feet) were identified and composed the cohort instrument. A total of 127 patients were included in the study from June 2006 until December 2013, which revealed 57% overall incidence of PSTP. The prediction model of PSTP development was obtained by Cox regression, and the significant variables identified were alcoholism, presence of metastases, radiotherapy, anthelmintic use, palliative chemotherapy and discomfort in the lower limbs. The results show that PSTP is a common finding in cancer patients during cancer chemotherapy.