Interactions of natural products and antimicrobial drugs: investigations of a dark matter in chemistry

Página do item simplificado
dc.creatorMarcus Vinícius Dias Souza
dc.creatorCleiton Gonçalvez Dias
dc.creatorPedro Henrique Ferreira-Marçal
dc.date.accessioned2024-09-25T21:08:42Z
dc.date.accessioned2025-09-09T01:21:50Z
dc.date.available2024-09-25T21:08:42Z
dc.date.issued2018-08-15
dc.format.mimetypepdf
dc.identifier.issn2069-5837
dc.identifier.urihttps://hdl.handle.net/1843/76877
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofBiointerface Research in Applied Chemistry
dc.rightsAcesso Aberto
dc.subjectProdutos naturais
dc.subjectInterações
dc.subjectProdutos com Ação Antimicrobiana
dc.subject.otherNatural Products
dc.subject.otherInteractions
dc.subject.otherAntimicrobial
dc.titleInteractions of natural products and antimicrobial drugs: investigations of a dark matter in chemistry
dc.typeArtigo de periódico
local.citation.epage3264
local.citation.issue3
local.citation.spage3259
local.citation.volume8
local.description.resumoBacterial infectious diseases are each time more difficult to manage due to the limited options of antimicrobial drugs and due to the multidrug resistance profile of pathogenic strains. Several works on natural products of vegetable sources have provided evidence of the antimicrobial potential of different phytomolecules such as flavonoids. Thus, they represent an important strategy to overcome the microbial resistance scenario. Beyond the use of natural products alone in popular medicine, they are commonly combined to synthetic drugs of different pharmacological groups such as antimicrobials in several ways, including interactions with industrially-manufactured or artisanally prepared phytotherapics, nutritional supplements, food, juices, and teas. Such interactions are often ignored in the clinical context. Synergistic interactions can improve treatment outcomes, however, enough evidences of efficacy and safety must be provided before being clinically used. Here, interactions of natural products with antimicrobial drugs against bacterial pathogens are discussed, aiming to provide contributions for advancements on the field towards a safe clinical use of such combinations. The data discussed here might open doors for improvements on phytotherapy for infectious bacterial diseases.
local.publisher.countryBrasil
local.publisher.departmentENG - DEPARTAMENTO DE ENGENHARIA ELÉTRICA
local.publisher.initialsUFMG
local.url.externahttps://biointerfaceresearch.com/?page_id=2421

Arquivos

Pacote original

Agora exibindo 1 - 1 de 1
Imagem de Miniatura
Nome:
Interactions of natural products and antimicrobial drugs- investigations of a dark matter in chemistry.pdf
Tamanho:
435.37 KB
Formato:
Adobe Portable Document Format
Baixar

Licença do pacote

Agora exibindo 1 - 1 de 1
Imagem de Miniatura
Nome:
License.txt
Tamanho:
1.99 KB
Formato:
Plain Text
Descrição:
Baixar

Coleções

Artigo de Periódico

Logo UFMG