Blood neuron cell-derived microparticles as potential biomarkers in Alzheimer’s disease

Página do item simplificado
dc.creatorCarolina Antunes Magalhães
dc.creatorHenrique Cerqueira Guimarães
dc.creatorMarco Túlio Gualberto Cintra
dc.creatorElvis C. C. Mateo
dc.creatorMaria Aparecida Bicalho
dc.creatorMaria Das Graças Carvalho
dc.creatorLirlândia P. Sousa
dc.creatorPaulo Caramelli
dc.creatorKarina Braga Gomes
dc.creatorFernanda M. Campos
dc.creatorCristina M. G. Loures
dc.creatorVanessa Gomes Fraga
dc.creatorAna Carolina R. de Oliveira
dc.creatorAmanda c Chaves
dc.creatorNatália Pessoa Rocha
dc.creatorLeonardo Cruz de Souza
dc.creatorRaphael d Maia
dc.date.accessioned2023-08-07T21:28:11Z
dc.date.accessioned2025-09-08T22:53:18Z
dc.date.available2023-08-07T21:28:11Z
dc.date.issued2018-03-09
dc.format.mimetypepdf
dc.identifier.doihttps://doi.org/10.1515/cclm-2018-0483
dc.identifier.issn1434-6621
dc.identifier.urihttps://hdl.handle.net/1843/57582
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofClinical Chemistry and Laboratory Medicine
dc.rightsAcesso Restrito
dc.subjectDoença de Alzheimer
dc.subjectDisfunção Cognitiva
dc.subjectBiomarcadores
dc.subject.otherAlzheimer’s disease
dc.subject.otherCognitive Dysfunction
dc.subject.otherBiomarkers
dc.titleBlood neuron cell-derived microparticles as potential biomarkers in Alzheimer’s disease
dc.typeArtigo de periódico
local.citation.epagee80
local.citation.issue5
local.citation.spagee77
local.citation.volume57
local.description.resumoAlzheimer’s disease (AD) is the most frequent cause of dementia, associated with a significant and progressive loss of both cognitive and functional performance [1].Microparticles (MPs) are microvesicles, ranging from 0.1 to 1 µm, released from the cell membrane during its activation and apoptosis. They are involved in cell-cell communication transferring cyto/nuclear proteins, DNA, mRNA and miRNA [2, 3]. Considering that MPs are involved in neuroinflammation and hemostasis, and that levels of several vascular and inflammatory factors were reported to be increased in patients with AD [4], we hypothesized that plasmatic MPs levels (platelet, leukocyte, endothe lial, neuron cell-derived MPs and MPs that express tissue factor [TF]) may be potential biomarkers to AD diagnosis.
local.identifier.orcid0000-0003-3089-655x
local.publisher.countryBrasil
local.publisher.departmentFAR - DEPARTAMENTO DE ANÁLISES CLÍNICAS E TOXICOLÓGICAS
local.publisher.departmentMED - DEPARTAMENTO DE CLÍNICA MÉDICA
local.publisher.initialsUFMG
local.url.externahttps://www.degruyter.com/document/doi/10.1515/cclm-2018-0483/html

Arquivos

Licença do pacote

Agora exibindo 1 - 1 de 1
Imagem de Miniatura
Nome:
License.txt
Tamanho:
1.99 KB
Formato:
Plain Text
Descrição:
Baixar

Coleções

Artigo de Periódico

Logo UFMG