Cytotoxicity of two self-adhesive resin cements and their interference in the phagocytic activity of murine macrophages
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Universidade Federal de Minas Gerais
Descrição
Tipo
Artigo de periódico
Título alternativo
Citotoxicidade de dois cimentos resinosos autoadesivos e sua interferência na atividade fagocítica de macrófagos murinos
Primeiro orientador
Membros da banca
Resumo
Objectives: This study aimed to evaluate in vitro the effects of the self-adhesive resin cements RelyX U200 (3M ESPE) and seT PP (SDI Limited) on murine macrophages and the interference of the photoactivation. Materials and Methods: Cell viability assays, cell adherence, yeast phagocytosis of Saccharomyces boulardii and production of reactive oxygen species (ROS) were performed in the presence of capillaries containing the respective self-adhesive cement when photoactivated or not. Results: After long periods of contact, both types of cements, when not photoactivated, are more cytotoxic for macrophages. The seT PP cement when only chemically activated seems to interfere more negatively in the process of phagocytosis of yeasts S. boulardii. Both types of cements interfere in the cell adhesion process, independent of photoactivation. None of the types of cements tested was able to induce the production of ROS. Conclusions: Our results highlight the great importance of the photoactivation of selfadhesive resin cements in the dental clinic, since RelyX U200, when photoactivated, presented the best results within the evaluated parameters.
Abstract
Assunto
Citotoxicidade, Macrófagos, Cimentos dentários, Cimentos de resina
Palavras-chave
Cytotoxicity, Macrophages, Dental cement, Resin cement
Citação
Curso
Endereço externo
https://rde.ac/DOIx.php?id=10.5395/rde.2022.47.e31