Cytotoxicity of two self-adhesive resin cements and their interference in the phagocytic activity of murine macrophages

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dc.creatorDanilo Couto da Silva
dc.creatorLeonardo Gomes Vaz
dc.creatorWarley Luciano Fonseca Tavares
dc.creatorLeda Quercia Vieira
dc.creatorRicardo Reis de Oliveira
dc.creatorAntônio Paulino Ribeiro Sobrinho
dc.date.accessioned2023-10-27T21:08:22Z
dc.date.accessioned2025-09-09T00:17:38Z
dc.date.available2023-10-27T21:08:22Z
dc.date.issued2022
dc.description.sponsorshipCNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológico
dc.description.sponsorshipFAPEMIG - Fundação de Amparo à Pesquisa do Estado de Minas Gerais
dc.description.sponsorshipCAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
dc.format.mimetypepdf
dc.identifier.doihttps://doi.org/10.5395/rde.2022.47.e31
dc.identifier.issn2234-7666
dc.identifier.urihttps://hdl.handle.net/1843/60196
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofRestorative Dentistry & Endodontics
dc.rightsAcesso Aberto
dc.subjectCitotoxicidade
dc.subjectMacrófagos
dc.subjectCimentos dentários
dc.subjectCimentos de resina
dc.subject.otherCytotoxicity
dc.subject.otherMacrophages
dc.subject.otherDental cement
dc.subject.otherResin cement
dc.titleCytotoxicity of two self-adhesive resin cements and their interference in the phagocytic activity of murine macrophages
dc.title.alternativeCitotoxicidade de dois cimentos resinosos autoadesivos e sua interferência na atividade fagocítica de macrófagos murinos
dc.typeArtigo de periódico
local.citation.issue3
local.citation.volume47
local.description.resumoObjectives: This study aimed to evaluate in vitro the effects of the self-adhesive resin cements RelyX U200 (3M ESPE) and seT PP (SDI Limited) on murine macrophages and the interference of the photoactivation. Materials and Methods: Cell viability assays, cell adherence, yeast phagocytosis of Saccharomyces boulardii and production of reactive oxygen species (ROS) were performed in the presence of capillaries containing the respective self-adhesive cement when photoactivated or not. Results: After long periods of contact, both types of cements, when not photoactivated, are more cytotoxic for macrophages. The seT PP cement when only chemically activated seems to interfere more negatively in the process of phagocytosis of yeasts S. boulardii. Both types of cements interfere in the cell adhesion process, independent of photoactivation. None of the types of cements tested was able to induce the production of ROS. Conclusions: Our results highlight the great importance of the photoactivation of selfadhesive resin cements in the dental clinic, since RelyX U200, when photoactivated, presented the best results within the evaluated parameters.
local.identifier.orcidhttps://orcid.org/0000-0003-1782-2185
local.identifier.orcidhttps://orcid.org/0000-0001-7217-1325
local.identifier.orcidhttps://orcid.org/0000-0003-2077-927X
local.identifier.orcidhttps://orcid.org/0000-0001-5481-9618
local.identifier.orcidhttps://orcid.org/0000-0001-8397-9557
local.identifier.orcidhttps://orcid.org/0000-0002-3598-7592
local.publisher.countryBrasil
local.publisher.departmentFAO - DEPARTAMENTO DE ODONTOLOGIA RESTAURADORA
local.publisher.departmentICB - DEPARTAMENTO DE BIOQUÍMICA E IMUNOLOGIA
local.publisher.initialsUFMG
local.url.externahttps://rde.ac/DOIx.php?id=10.5395/rde.2022.47.e31

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