Efficacy of B-lactam/B-lactamase inhibitor combinations for the treatment of bloodstream infection due to extended-spectrum B-lactamase-producing enterobacteriaceae in hematological patients with neutropenia

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dc.creatorCarlotagudiol
dc.creatorPilar Martín-dávila
dc.creatorAlison Freifeld
dc.creatorLucía Gómez
dc.creatorThomas Gottlieb
dc.creatorMercè Gurguí
dc.creatorFabián Herrera
dc.creatorAdriana Manzur
dc.creatorGeorg Maschmeyer
dc.creatorYolanda Meije
dc.creatorMiguel Montejo
dc.creatorCristina Royo-cebrecos
dc.creatorMaddalena Peghin
dc.creatorJesús Rodríguez-baño
dc.creatorIsabel Ruiz-camps
dc.creatorTeresa c. Sukiennik
dc.creatorCristian Tebe
dc.creatorJordi Carratalà
dc.creatorEdson Abdala
dc.creatorMurat Akova
dc.creatorRocío Álvarez
dc.creatorGuillermo Maestro-de la Calle
dc.creatorAngela Cano
dc.creatorCarlos Cervera
dc.creatorWanessa Trindade Clemente
dc.date.accessioned2023-07-03T19:25:53Z
dc.date.accessioned2025-09-09T00:35:12Z
dc.date.available2023-07-03T19:25:53Z
dc.date.issued2017-05-07
dc.format.mimetypepdf
dc.identifier.doi10.1128/aac.00164-17
dc.identifier.issn00664804
dc.identifier.urihttps://hdl.handle.net/1843/55695
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofAntimicrobial Agents and Chemotherapy
dc.rightsAcesso Aberto
dc.subjectSepse
dc.subjectNeutropenia
dc.subjectInibidores de beta-Lactamases
dc.subject.otherESBLs
dc.subject.otherBloodstream infection
dc.subject.otherNeutropenia
dc.subject.otherbeta-lactam/beta-lactamase inhibitors
dc.subject.otherInibidores de beta-Lactamases
dc.titleEfficacy of B-lactam/B-lactamase inhibitor combinations for the treatment of bloodstream infection due to extended-spectrum B-lactamase-producing enterobacteriaceae in hematological patients with neutropenia
dc.typeArtigo de periódico
local.citation.epagee00164-17
local.citation.issue8
local.citation.spageAAC.00164-17
local.citation.volume61
local.description.resumoß-Lactam/ß-lactamase inhibitors (BLBLIs) were compared to carbapenems in two cohorts of hematological neutropenic patients with extended-spectrum- -lactamase (ESBL) bloodstream infection (BSI): the empirical therapy cohort (174 patients) and the definitive therapy cohort (251 patients). The 30-day case fatality rates and other secondary outcomes were similar in the two therapy groups of the two cohorts and also in the propensity-matched cohorts. BLBLIs might be carbapenem sparing alternatives for the treatment of BSI due to ESBLs in these patients.
local.identifier.orcidhttps://orcid.org/0000-0003-0848-3740
local.publisher.countryBrasil
local.publisher.departmentMED - DEPARTAMENTO DE PROPEDÊUTICA COMPLEMENTAR
local.publisher.initialsUFMG
local.url.externahttps://journals.asm.org/doi/10.1128/aac.00164-17

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