Does the use of intra-alveolar chlorhexidine gel reduces the rate of alveolar osteitis, pain, edema and trismus after the extraction of lower third molars? A meta analysis
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Universidade Federal de Minas Gerais
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Artigo de periódico
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Membros da banca
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Objective: The aim was to evaluate the efficacy of the use of intra-alveolar chlorhexidine gel in preventing alveolar osteitis and reducing edema, pain and trismus after the extraction of lower third molars. Methods: The searches were performed in the following databases: PubMed, The Cochrane Library, Elsevier Science Direct, and Ovid MEDLINE up to October 2015. The risk of bias of the included studies was assessed using the Cochrane Collaboration’s tool. The following data, when available, were included in the final analysis of the selected articles: author, year of publication, country of origin, study design, type of treatment instituted, average age, number of patients, follow-up, pain, edema, trismus, and alveolar osteitis. Results: Eleven studies were included for analysis. In the alveolar osteitis variable, 6 studies were included in the meta-analysis. In this analysis, the use of intra-alveolar chlorhexidine gel showed better results than the use of placebo (95% CI = 0.62 − 0.89; p = 0.002). For the pain variable, 3 studies were included in the meta-analysis, which were favorable to the use of intra-alveolar chlorhexidine gel (95% CI = (−0.69) − (−0.27) p < 0.001). For edema and trismus variables, the results were not statistically significant. Conclusion: The results of the analysis suggest that the use of intra-alveolar chlorhexidine gel after surgical removal of mandibular third molars reduces pain and decreases the prevalence of alveolar osteitis.
Abstract
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Chlorhexidine, Dry socket, Molar, third, Surgery, oral, Meta-analysis
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Chlorhexidine, Alveolar osteitis, Third molar, Oral surgery
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https://www.sciencedirect.com/science/article/pii/S2212555817301254