Does the use of intra-alveolar chlorhexidine gel reduces the rate of alveolar osteitis, pain, edema and trismus after the extraction of lower third molars? A meta analysis

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dc.creatorAnna Catharina Vieira Armond
dc.creatorLara Moreira Jalles Milani
dc.creatorJussara de Fátima Barbosa Fonseca
dc.creatorCarolina de Castro Martins
dc.creatorSaulo Gabriel Moreira Falci
dc.date.accessioned2024-01-24T20:01:55Z
dc.date.accessioned2025-09-09T00:07:57Z
dc.date.available2024-01-24T20:01:55Z
dc.date.issued2017-11
dc.identifier.doihttps://doi.org/10.1016/j.ajoms.2017.06.012
dc.identifier.issn2212-5566
dc.identifier.urihttps://hdl.handle.net/1843/63297
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofJournal of Oral and Maxillofacial Surgery, Medicine, and Pathology
dc.rightsAcesso Restrito
dc.subjectChlorhexidine
dc.subjectDry socket
dc.subjectMolar, third
dc.subjectSurgery, oral
dc.subjectMeta-analysis
dc.subject.otherChlorhexidine
dc.subject.otherAlveolar osteitis
dc.subject.otherThird molar
dc.subject.otherOral surgery
dc.titleDoes the use of intra-alveolar chlorhexidine gel reduces the rate of alveolar osteitis, pain, edema and trismus after the extraction of lower third molars? A meta analysis
dc.typeArtigo de periódico
local.citation.epage499
local.citation.issue6
local.citation.spage491
local.citation.volume29
local.description.resumoObjective: The aim was to evaluate the efficacy of the use of intra-alveolar chlorhexidine gel in preventing alveolar osteitis and reducing edema, pain and trismus after the extraction of lower third molars. Methods: The searches were performed in the following databases: PubMed, The Cochrane Library, Elsevier Science Direct, and Ovid MEDLINE up to October 2015. The risk of bias of the included studies was assessed using the Cochrane Collaboration’s tool. The following data, when available, were included in the final analysis of the selected articles: author, year of publication, country of origin, study design, type of treatment instituted, average age, number of patients, follow-up, pain, edema, trismus, and alveolar osteitis. Results: Eleven studies were included for analysis. In the alveolar osteitis variable, 6 studies were included in the meta-analysis. In this analysis, the use of intra-alveolar chlorhexidine gel showed better results than the use of placebo (95% CI = 0.62 − 0.89; p = 0.002). For the pain variable, 3 studies were included in the meta-analysis, which were favorable to the use of intra-alveolar chlorhexidine gel (95% CI = (−0.69) − (−0.27) p < 0.001). For edema and trismus variables, the results were not statistically significant. Conclusion: The results of the analysis suggest that the use of intra-alveolar chlorhexidine gel after surgical removal of mandibular third molars reduces pain and decreases the prevalence of alveolar osteitis.
local.publisher.countryBrasil
local.publisher.departmentFAO - DEPARTAMENTO DE ODONTOPEDIATRIA E ORTODONTIA
local.publisher.initialsUFMG
local.url.externahttps://www.sciencedirect.com/science/article/pii/S2212555817301254

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