Nódulo abdominal com células neoplásicas originadas de carcinoma urotelial e extravasamento em cavidade – Relato de caso

Abstract

Urothelial carcinoma is the most common bladder neoplasm in dogs, occurring in 75% to 90% of primary neoplasms of this organ. Typically infiltrative and of intermediate to high grade, the tumor has a high tendency to metastasize, and its early diagnosis is hindered by non-specific clinical signs. The presence of hematuria, stranguria, pollakiuria, and dysuria, often associated with urinary tract infections, can be detected through laboratory tests, aiding in early diagnosis and better prognosis. The risk of tumor dissemination after diagnostic and therapeutic procedures, especially surgical ones, emphasizes the importance of less invasive techniques. This study reports a case of urothelial carcinoma in a dog with abdominal implantation/metastasis, diagnosed by clinical cytology after the removal of a bladder nodule. During treatment with chemotherapy and immunotherapy, disease progression was monitored by laboratory tests, revealing new abdominal nodules and confirming the unfavorable diagnosis. The cytology of these nodules showed malignant features consistent with those observed in the primary tumor, demonstrating the importance of laboratory tests in early diagnosis and monitoring during oncological treatment.