Prevalence and determinants of depressive symptoms in patients with chagas cardiomyopathy and predominantly preserved cardiac function

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dc.creatorWhesley Tanorsilva
dc.creatorManoel Otávio da Costa Rocha
dc.creatorMatheus Ribeiro Ávila
dc.creatorLucas Frois Fernandes de Oliveira
dc.creatorPedro Henrique Scheidt Figueiredo
dc.creatorVanessa Pereira Lima
dc.creatorAlessandra de Carvalho Bastone
dc.creatorFábio Silva Martins da Costa
dc.creatorMauro Felippe Felix Mediano
dc.creatorHenrique Silveira Costa
dc.date.accessioned2024-01-10T20:29:21Z
dc.date.accessioned2025-09-09T00:11:12Z
dc.date.available2024-01-10T20:29:21Z
dc.date.issued2020
dc.format.mimetypepdf
dc.identifier.doi10.1590/0037-8682-0123-2020
dc.identifier.issn16789849
dc.identifier.urihttps://hdl.handle.net/1843/62551
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofRevista da Sociedade Brasileira de Medicina Tropical
dc.rightsAcesso Aberto
dc.subjectChagas disease.
dc.subjectChagas cardiomyopathy
dc.subjectDepressive Disorder
dc.subjectExercise Test
dc.subjectActivities of Daily Living
dc.subjectMental Health
dc.subject.otherChagas disease.
dc.subject.otherChagas cardiomyopathy
dc.subject.otherDepressive Disorder
dc.subject.otherExercise Test
dc.subject.otherActivities of Daily Living
dc.subject.otherMental Health
dc.titlePrevalence and determinants of depressive symptoms in patients with chagas cardiomyopathy and predominantly preserved cardiac function
dc.typeArtigo de periódico
local.citation.epage7
local.citation.issue(e20200123
local.citation.spage1
local.citation.volume53
local.description.resumoIntroduction: Chagas cardiomyopathy (ChC) is highly stigmatized, and the presence of depressive symptoms may be a common feature. However, its determinants remain unclear. Therefore, the present study aimed to verify the prevalence of depression and the clinical, echocardiographic, functional, and quality of life factors associated with depressive symptoms in patients with ChC and predominantly preserved cardiac function. Methods: Thirty-five patients with ChC (aged 40 to 60 years, 66% men, NYHA I-III) were evaluated by echocardiography, cardiopulmonary exercise testing, 6-minute walk test (6MWT), and Mini-Mental State Examination. Physical activity level was assessed using the Human Activity Profile (HAP) and health-related quality of life was assessed using the Short-Form Health Survey (SF-36). Depressive symptoms were evaluated using the Beck Depression Inventory. A cutoff point greater than 9 was indicative of depression. Results: Depression was detected in 13 patients (37%). In the univariate analysis, female sex, NYHA functional class, body mass index, HAP score, mental summary of SF-36, peak oxygen uptake, and 6MWT distance were associated with depressive symptoms. The final model showed that only the HAP score (B = -0.533; 95% confidence interval [CI]: -0.804 to -0.262) and SF-36 mental summary (B = -0.269; 95% CI: -0.386 to -0.153) remained as independent predictors of depressive symptoms in patients with ChC. Conclusions: Depression was prevalent in patients with ChC and predominantly preserved cardiac function. Physical activity and mental health were independent risk factors for depressive symptoms.
local.publisher.countryBrasil
local.publisher.departmentMED - DEPARTAMENTO DE CLÍNICA MÉDICA
local.publisher.initialsUFMG
local.url.externahttps://doi.org/10.1590/0037-8682-0123-2020

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