Hipoadrenocorticismo primário em cão - relato de caso

Abstract

Hypoadrenocorticism is an endocrine disease that affects the adrenal glands, characterized by low secretion of mineralocorticoids and/or glucocorticoids. It presents nonspecific clinical signs, which makes it a differential diagnosis of several diseases and, sometimes, underdiagnosed due to the lack of knowledge of the disease by some veterinarians. The present work reports a case of primary hypoadrenocorticism in a three-year-old, male, mixed-breed dog treated at the HV UFMG. During anamnesis, the tutor reported as main complaints the occurrence of weakness, incoordination, vomiting and anorexia. Also reported the history of having had a consultation with another professional and having been diagnosed with renal failure. During physical examination, bradycardia, pale mucous membranes and hypothermia were noted. On hematological examinations, he had normocytic normochromic anemia and azotemia. In abdominal ultrasound, renal changes and hypotrophied left adrenal. At the time, the animal was hospitalized and, after hospital admission, hypotension, normoglycemia and progressive clinical improvement were observed. In blood gas analysis, the patient showed hyperkalemia and hyponatremia and in a new biochemical profile, a reduction in serum levels of urea and creatinine. In view of the clinical findings, a basal cortisol measurement was requested, with a result below the reference values and primary hypoadrencorticism confirmed. As maintenance therapy, prednisolone and fludrocortisone were prescribed. The patient showed complete remission of clinical signs and improvement of changes in laboratory tests after starting treatment.