Ginger (Zingiber officinale rosc.) ameliorated metabolic and inflammatory dysfunction induced by high-refined carbohydrate-containing diet in mice

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dc.creatorCintia Tabaral Oliveira
dc.creatorDébora Romualdo Lacerda
dc.creatorMarina Campos Zicker
dc.creatorLaís Bhering Martins
dc.creatorMauro Martins Teixeira
dc.creatorRaquel Linhares Bello de Araújo
dc.creatorAdaliene Versiani Matos Ferreira
dc.date.accessioned2022-05-13T20:52:25Z
dc.date.accessioned2025-09-09T01:06:19Z
dc.date.available2022-05-13T20:52:25Z
dc.date.issued2019-01
dc.description.sponsorshipCNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológico
dc.description.sponsorshipCAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
dc.description.sponsorshipOutra Agência
dc.identifier.doihttps://doi.org/10.1089/jmf.2018.0062
dc.identifier.issn1096-620X
dc.identifier.urihttps://hdl.handle.net/1843/41659
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofJournal of Medicinal Food
dc.rightsAcesso Restrito
dc.subjectGengibre
dc.subjectObesidade
dc.subjectCamundongos
dc.subject.otherCytokines
dc.subject.otherGingerol
dc.subject.otherInflammation
dc.subject.otherObesity
dc.titleGinger (Zingiber officinale rosc.) ameliorated metabolic and inflammatory dysfunction induced by high-refined carbohydrate-containing diet in mice
dc.typeArtigo de periódico
local.citation.epage8
local.citation.issue1
local.citation.spage1
local.citation.volume22
local.description.resumoThis study aimed to evaluate the effects and the mechanisms of ginger extract intake in the adiposity gain, metabolic and inflammatory disturbances induced by a high-refined carbohydrate (HC) diet in mice. Ginger extract at doses of 200, 600, and 1800 mg/kg was supplemented in the daily food of obese Balb/c mice during an 8-week experiment. Our findings indicate that consumption of high doses of ginger extracts prevents the increase of adiposity induced by HC diet, improves lipid profile, and promotes decrease of inflammatory markers in mice. We showed that ginger addition to HC diet leads to decrease in the recruitment of cells visualized in vivo in the microvasculature of adipose tissue, decrease of inflammatory cytokines, and increase of adiponectin serum levels. These results indicate that the consumption of ginger decreases the negative metabolic consequences induced by HC diet.
local.publisher.countryBrasil
local.publisher.departmentFAR - DEPARTAMENTO DE ALIMENTOS
local.publisher.initialsUFMG
local.url.externahttps://www.liebertpub.com/doi/full/10.1089/jmf.2018.0062

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