Periodontal, microbiological and immunological clinical conditions in a 9-year-old child with localized advanced periodontitis: case reports in a 18-mouth follow-up
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Universidade Federal de Minas Gerais
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Artigo de periódico
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Abstract : The objective of this study is to report a clinical case of a 9 year old child diagnosed with localized
advanced and high risk periodontitis through periodontal clinical parameters and radiographic,
microbiological and immunological exams. In the clinical examination was observed probing depth alteration
of the four first molars, although there was no plaque compatible with the periodontal condition. Radiographic
examination revealed angular bone loss in the mesial sites of elements 26, 36 and expressively of 16.
Microbiological and immunological tests were performed from the collection of crevicular gingival fluid and
saliva. Thus, total bacterial load count and specific bacterial levels of Aggregatibacter actinomycete mcomitans; Tannerella forsythia, Porphyromonas gingivalis; Treponema denticola; Prevotella intermedia and
Actinomyces naeslundii were performed by qPCR (Polymerase Chain Reaction - real time), while levels of the
biomarkers Interleukin 10 (IL-10), Interleukin 6 (IL-6), Interleukin beta (IL-β), Metaloproteinase of matrix-8
(MMP-8) and tumor necrosis factor alpha (TNF-α) by ELISA. The proposed treatment included non-surgical
and surgical periodontal therapy and antimicrobial use. During the 18 month follow-up of the patient, the
mechanical and chemical periodontal treatment promoted a significant improvement in all clinical and
radiographic periodontal parameters and positively influenced the patient's bacterial and immunological
profile.
Abstract
Assunto
Aggressive periodontitis, Periodontitis, Anti-bacterial agents, Microbiology, Immune system, Bacteria, Biomarkers, Matrix metalloproteinase 8, Tumor necrosis factor-alpha, Therapeutics, Surgery, oral, Bone resorption
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Advanced Periodontitis acesso aberto Periodontal, microbiological and immunological clinical conditions in a 9-year-old child with localized advanced periodontitis: case reports in a 18-mouth follow-up busca dia 18/07/2024 hora 17 e 49, children Keywords: Periodontitis, Localized aggressive periodontitis, Bone graft, Antibiotic therapy, Microbiology Arc journal of clinical case reports, immunological Arc Journal of Clinical Case Reports
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https://www.arcjournals.org/journal-of-clinical-case-reports/volume-4-issue-2/