Periodontal, microbiological and immunological clinical conditions in a 9-year-old child with localized advanced periodontitis: case reports in a 18-mouth follow-up

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dc.creatorBruna Lara França
dc.creatorAmanda Almeida Costa
dc.creatorLuis Otávio de Miranda Cota
dc.creatorFernando de Oliveira Costa
dc.date.accessioned2024-07-19T20:16:52Z
dc.date.accessioned2025-09-09T01:33:14Z
dc.date.available2024-07-19T20:16:52Z
dc.date.issued2018
dc.identifier.doihttp://dx.doi.org/10.20431/2455-9806.040100
dc.identifier.issn2455-9806
dc.identifier.urihttps://hdl.handle.net/1843/71085
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofArc Journal of Clinical Case Reports
dc.rightsAcesso Aberto
dc.subjectAggressive periodontitis
dc.subjectPeriodontitis
dc.subjectAnti-bacterial agents
dc.subjectMicrobiology
dc.subjectImmune system
dc.subjectBacteria
dc.subjectBiomarkers
dc.subjectMatrix metalloproteinase 8
dc.subjectTumor necrosis factor-alpha
dc.subjectTherapeutics
dc.subjectSurgery, oral
dc.subjectBone resorption
dc.subject.otherAdvanced Periodontitis acesso aberto Periodontal, microbiological and immunological clinical conditions in a 9-year-old child with localized advanced periodontitis: case reports in a 18-mouth follow-up busca dia 18/07/2024 hora 17 e 49
dc.subject.otherchildren Keywords: Periodontitis, Localized aggressive periodontitis, Bone graft, Antibiotic therapy
dc.subject.otherMicrobiology Arc journal of clinical case reports
dc.subject.otherimmunological Arc Journal of Clinical Case Reports
dc.titlePeriodontal, microbiological and immunological clinical conditions in a 9-year-old child with localized advanced periodontitis: case reports in a 18-mouth follow-up
dc.typeArtigo de periódico
local.citation.epage20
local.citation.issue2
local.citation.spage13
local.citation.volume4
local.description.resumoAbstract : The objective of this study is to report a clinical case of a 9 year old child diagnosed with localized advanced and high risk periodontitis through periodontal clinical parameters and radiographic, microbiological and immunological exams. In the clinical examination was observed probing depth alteration of the four first molars, although there was no plaque compatible with the periodontal condition. Radiographic examination revealed angular bone loss in the mesial sites of elements 26, 36 and expressively of 16. Microbiological and immunological tests were performed from the collection of crevicular gingival fluid and saliva. Thus, total bacterial load count and specific bacterial levels of Aggregatibacter actinomycete mcomitans; Tannerella forsythia, Porphyromonas gingivalis; Treponema denticola; Prevotella intermedia and Actinomyces naeslundii were performed by qPCR (Polymerase Chain Reaction - real time), while levels of the biomarkers Interleukin 10 (IL-10), Interleukin 6 (IL-6), Interleukin beta (IL-β), Metaloproteinase of matrix-8 (MMP-8) and tumor necrosis factor alpha (TNF-α) by ELISA. The proposed treatment included non-surgical and surgical periodontal therapy and antimicrobial use. During the 18 month follow-up of the patient, the mechanical and chemical periodontal treatment promoted a significant improvement in all clinical and radiographic periodontal parameters and positively influenced the patient's bacterial and immunological profile.
local.identifier.orcidhttps://orcid.org/0000-0001-9273-376X
local.publisher.countryBrasil
local.publisher.departmentFAO - DEPARTAMENTO DE CLÍNICA
local.publisher.initialsUFMG
local.url.externahttps://www.arcjournals.org/journal-of-clinical-case-reports/volume-4-issue-2/

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