Extratos de fungos na inibição da eclodibilidade e do desenvolvimento larval de Haemonchus contortus

Abstract

The sheep industry has an outstanding position in the commercial exploitation and subsistence. However, the practices adopted in farms contribute to the occurrence of parasitic diseases, which constitute a major obstacle to this productive sector. The use of anthelmintics trade in animals, besides being costly, allows selection for resistance to bases anthelmintic. These waste products can still infect man, remaining in the meat and milk of sheep, or in the environment. The fungi are considered promising sources of secondary metabolites for therapeutic use. This study aimed to evaluate the efficacy anthelmintic basidiomycete and ascomycete fungi in vitro in control of Haemonchus contortus under different preparation methods. Tests were conducted inhibition hatchability (IH) and inhibition of larval development (ILD) to determine the efficacy of crude powder, aqueous and ethanolic extracts of Agaricus brasiliensis, and the filtrate and ethanolic extract of Aspergillus terreus, Paecilomyces sp. Trichoderma longibrachiatum. The filtrate and the ethanol extract of A. brasiliensis showed 100% efficacy in IH contortus at all concentrations tested. The crude powder showed an efficacy of 98.39% in ILD. For the ascomycetes, it was found efficacies in IH greater than 96% for the ethanol extracts. However, the effective concentrations varied as afunction of the genera of fungi. In ILD, the filtrate of Trichoderma longibrachiatum was effective at the concentration 0.79 mg / g, with an efficiency of 92.8%. It is concluded that fungi studied have promising potential alternative to the control of Haemonchus contortus in sheep.