Association between depression and periodontitis: a systematic review and meta-analysis
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Universidade Federal de Minas Gerais
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Aim: The aim of this systematic review and meta-analysis was to assess the scientific evidence on the association between depression and periodontitis.
Methods: An electronic search was conducted in three databases until October 2015 (PROSPERO-CRD42014006451). Hand searches and grey literature were also included. Search retrieved 423 potentially studies. Two independent reviewers selected the studies, extracted data and assessed risk bias through a modified version of Newcastle-Ottawa scale. Meta-analysis was performed for the presence/absence of periodontitis (dichotomic). Summary effect measures and odds ratio (OR) 95% CI were calculated.
Results: After selecting the studies, 15 were included in the systematic review (eight cross-sectional, six case-control and one cohort study). Six studies reported that depression was associated with periodontitis, whereas nine studies did not. The majority of studies had low risk of bias by methodological quality assessment. Meta-analysis of seven cross-sectional studies showed no significant association between depression and periodontitis (OR = 1.03, 95% CI = 0.75-1.41).
Conclusion: Findings from the present systematic review showed a great heterogeneity among the studies and the summary effect measure of the meta-analysis cannot affirm an association between depression and periodontitis. Future studies with different designs in distinct populations should be conducted to investigate this association
Abstract
Assunto
Depression, Periodontitis, Systematic review, Network meta-analysis, Association
Palavras-chave
aggressive periodontitis; chronic periodontitis; depressive disorders.periodontal disease; periodontitis., nome revista Journal of clinical periodontology fao clínica, ortodontia busca dia 17 do mês 08 agosto ano 2023 assunto periodontite depression, fazer no dia 30 do 08 agosto ano 2023
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https://onlinelibrary.wiley.com/doi/10.1111/jcpe.12510