Probióticos para o tratamento de doenças neurológicas: uma revisão

Abstract

The intestinal microbiota term refers primarily to the bacterial community that normally resides in the human or animal intestine. The population exceeds in number eukaryotic cells comprising the adult human body in a comparative 1014 1013 CFU / g content. Recently, a new influence of the intestinal tract on the host has been described and called microflora-gut-brain axis, demonstrating the existence of one-way bi-directional involving neuronal routes (vagus nerve and enteric nervous system), humoral (cortisol) and immune (cytokine). It is believed that their imbalance may have consequences for the health of the gut and mind such as depression, autism and hepatic encephalopathy. Probiotics are defined as live microorganisms which when administered in adequate amounts confer a benefit to the health of the host. This study shows that the intervention in the microbial ecosystem associated with the human host with probiotic intake has great potential in the treatment of these pathologies.