Lymphomas Affecting the Sublingual Glands: A Clinicopathological Study

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dc.creatorGabriela Ribeiro de Araújo
dc.creatorHélder Antônio Rebelo Pontes
dc.creatorBruno Augusto Benevenuto de Andrade
dc.creatorCiro Dantas Soares
dc.creatorRicardo Santiago Gomez
dc.creatorFelipe Paiva Fonseca
dc.creatorAna Luísa Morais-Perdigão
dc.creatorCinthia Verónica Bardález Lopez de Cáceres
dc.creatorMárcio Ajudarte Lopes
dc.creatorJosé Manuel Aguirre-urizar
dc.creatorRoman Carlos
dc.creatorElena María José Román Tager
dc.creatorWillie F. P. Van Heerden
dc.creatorLiam Robinson
dc.date.accessioned2024-12-05T20:30:16Z
dc.date.accessioned2025-09-08T23:41:21Z
dc.date.available2024-12-05T20:30:16Z
dc.date.issued2023-03
dc.identifier.doihttps://doi.org/10.1007/s12105-022-01489-8
dc.identifier.issn1936-0568
dc.identifier.urihttps://hdl.handle.net/1843/78478
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofHead and Neck Pathology
dc.rightsAcesso Restrito
dc.subjectOdontologia
dc.subjectLinfoma
dc.subject.otherLinfoma
dc.subject.othercâncer de cabeça e pescoço
dc.subject.othercâncer bucal
dc.titleLymphomas Affecting the Sublingual Glands: A Clinicopathological Study
dc.typeArtigo de periódico
local.citation.epage164
local.citation.spage154
local.citation.volume17
local.description.resumoBackground Lymphomas afecting the sublingual glands are extremely rare and very few case reports are currently available. Therefore, the aim of the current study is to describe the clinicopathological features of a series of lymphomas involving the sublingual glands. Methods Cases diagnosed in four pathology services were assessed and the formalin-fxed parafn-embedded tissue blocks were retrieved for diagnosis confrmation. Clinical data were obtained from patients’ medical fles. Results We obtained seven cases of lymphomas in the sublingual glands, representing two follicular lymphomas, two difuse large B cell lymphomas not otherwise specifed (DLBCL NOS), two extranodal marginal zone B cell lymphoma of mucosa associated lymphoid tissue (MALT lymphomas) and one mantle cell lymphoma (MCL). In all cases the tumor cells infltrated the glandular parenchyma, although in two of them the neoplastic cells were located more superfcially and permeated the glandular acini and ducts. Clinically, the tumors presented as asymptomatic nodules and two patients (afected by DLBCL NOS and MCL) died, while the other fve patients remained alive at last follow-up. Conclusion Lymphomas afecting the sublingual glands are usually of the mature B cell lineage, often represent low-grade subtypes and may clinically resemble other more common lesions in the foor of the mouth like salivary gland tumors.
local.publisher.countryBrasil
local.publisher.departmentFAO - DEPARTAMENTO DE CLÍNICA
local.publisher.initialsUFMG
local.url.externahttps://link.springer.com/article/10.1007/s12105-022-01489-8#citeas

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