Prospective randomised clinical trial using autogenous bone or beta-tricalcium phosphate in maxillary sinus lifting: histological and tomographic results

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dc.creatorFernanda Brasil Daura Jorge Boos Lima
dc.creatorR.S. Pereira
dc.creatorSergio Monteiro Lima Junior
dc.creatorI.R. Garcia Junior
dc.creatorRoberta Okamoto
dc.creatorEduardo Hochuli-Vieira
dc.date.accessioned2025-03-20T10:31:42Z
dc.date.accessioned2025-09-09T01:09:06Z
dc.date.available2025-03-20T10:31:42Z
dc.date.issued2017-03
dc.format.mimetypepdf
dc.identifier.doihttps://doi.org/10.1016/j.ijom.2017.02.897
dc.identifier.issn0901-5027
dc.identifier.urihttps://hdl.handle.net/1843/80783
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofInternational Journal of Oral and Maxillofacial Surgery
dc.rightsAcesso Aberto
dc.subjectTartrate-resistant acid phosphatase
dc.subjectMouth floor
dc.subjectMaxillary sinus
dc.subjectBone and bones
dc.subjectResidual volume
dc.subjectImmunohistochemistry
dc.subjectOsteocalcin
dc.titleProspective randomised clinical trial using autogenous bone or beta-tricalcium phosphate in maxillary sinus lifting: histological and tomographic results
dc.typeArtigo de periódico
local.citation.issueSupplement 1
local.citation.spage266
local.citation.volume46
local.description.resumoObjectives: The aim of this study was to analyse the use of the beta-tricalcium phosphate (-TCP) ChronOS® and autogenous bone (AB) in maxillary sinus floor augmentation by compar ing computed tomography (CT), histological, histometric and immunohistochemical analysis. Methods: 12 consecutive patients underwent bilateral maxillary sinus grafting. One side of each patient was augmented with pure-TCP and the other sinus was augmented with pure autogenous bone. Patients had their sinus scanned for computed tomography (CT)seven and 180 day safter surgery for quantitative comparative analysis of residual volume after graft resorption and remodeling. Prior to implant placement, grafted material was collected from each sinus using a drilling mill for histological and histochemical analysis. Findings: CT volumetric analysis revealed no statistically signif icant difference between groups. Histological analysis revealed absorbing granules of-TCP being substituted by mature bone. Histomorphometric analysis showed the presence of 51.58% of newly formed bone in the-TCP group and 40.97% in the AB group. There was no statistical difference between the groups. Immunohistochemical evaluated the presence of osteocal cin, Runt-related transcription factor2(RUNX2),tartrate-resistant acidic phosphatase(TRAP)and vascular end endothelial growth factor (VEGF). Osteocalcin and VEGF were expressed in both groups with similar intensity. TRAP showed a low expression in both groups. RUNX2 was observed only in AB group. Conclusions:Autogenous bone has superior osteoinductive prop erties. ChronOS® isa biocompatible and osteoconductive material with similar clinical results to the autogenous bone in this proposed model, even without osteoinductive properties.
local.identifier.orcidhttps://orcid.org/0000-0003-2847-9685
local.identifier.orcidhttps://orcid.org/0000-0003-0022-2538
local.identifier.orcidhttps://orcid.org/0000-0001-9246-4571
local.identifier.orcidhttps://orcid.org/0000-0003-4040-9313
local.publisher.countryBrasil
local.publisher.departmentFAO - DEPARTAMENTO DE CLÍNICA
local.publisher.initialsUFMG
local.url.externahttps://www.ijoms.com/article/S0901-5027(17)30958-X/fulltext

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