Mesoscopic model confirms strong base pair metal mediated bonding for T–Hg2+ –T and weaker for C–Ag+–C

Página do item simplificado
dc.creatorLuciano Gabriel Silva
dc.creatorGerald Weber
dc.date.accessioned2025-02-25T17:57:09Z
dc.date.accessioned2025-09-09T01:34:27Z
dc.date.available2025-02-25T17:57:09Z
dc.date.issued2022
dc.description.sponsorshipCNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológico
dc.description.sponsorshipCAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
dc.format.mimetypepdf
dc.identifier.doihttps://doi.org/10.1016/j.cplett.2022.139847
dc.identifier.issn1873-4448
dc.identifier.urihttps://hdl.handle.net/1843/80427
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofChemical Physics Letters
dc.rightsAcesso Aberto
dc.subjectBiofísica
dc.subjectDNA
dc.subjectHidrogênio
dc.subject.otherMetal-mediated DNA
dc.subject.otherMetallo-base-pair
dc.subject.otherPeyrard–Bishop DNA model
dc.subject.otherDNA stability
dc.subject.otherHydrogen bonds
dc.subject.otherStacking interaction
dc.titleMesoscopic model confirms strong base pair metal mediated bonding for T–Hg2+ –T and weaker for C–Ag+–C
dc.typeArtigo de periódico
local.citation.epage6
local.citation.spage1
local.citation.volume803
local.description.resumoMetal mediated DNA are mismatches where a metal ion bridges the base pairs and are of interest for biosensors. Here, we study T–Hg2+–T, which is known to be stabilized by base pair metal mediated bonds, and C–Ag+–C whose stabilization mechanism is less well understood. We use a mesoscopic model and published melting temperatures of sequences containing CC or TT mismatches in the presence of the metal ions. For T–Hg2+–T we obtain a strong base pair bond potential and moderate one for C–Ag+–C, only one stacking potential for each configuration is stronger than usual.
local.identifier.orcidhttps://orcid.org/0000-0002-2935-1571
local.publisher.countryBrasil
local.publisher.departmentICX - DEPARTAMENTO DE FÍSICA
local.publisher.initialsUFMG
local.url.externahttps://www.sciencedirect.com/science/article/pii/S0009261422005139

Arquivos

Pacote original

Agora exibindo 1 - 1 de 1
Imagem de Miniatura
Nome:
Mesoscopic model confirms strong base pair metal mediated bonding for.pdf
Tamanho:
585.29 KB
Formato:
Adobe Portable Document Format
Baixar

Licença do pacote

Agora exibindo 1 - 1 de 1
Imagem de Miniatura
Nome:
License.txt
Tamanho:
1.99 KB
Formato:
Plain Text
Descrição:
Baixar

Coleções

Artigo de Periódico

Logo UFMG