On the application of 3d metals for C-H activation toward bioactive compounds: the key step for the synthesis of silver bullets

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dc.creatorRenato Lúcio de Carvalho
dc.creatorAmanda Silva de Miranda
dc.creatorMateus Pena Nunes
dc.creatorRoberto da Silva Gomes
dc.creatorGuilherme Augusto de Melo Jardim
dc.creatorEufrânio Nunes da Silva Junior
dc.date.accessioned2023-07-03T21:26:08Z
dc.date.accessioned2025-09-09T01:00:08Z
dc.date.available2023-07-03T21:26:08Z
dc.date.issued2021
dc.description.sponsorshipCNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológico
dc.description.sponsorshipFAPEMIG - Fundação de Amparo à Pesquisa do Estado de Minas Gerais
dc.description.sponsorshipCAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
dc.description.sponsorshipOutra Agência
dc.format.mimetypepdf
dc.identifier.doihttps://doi.org/10.3762/bjoc.17.126
dc.identifier.issn18605397
dc.identifier.urihttps://hdl.handle.net/1843/55706
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofBeilstein Journal of Organic Chemistry
dc.rightsAcesso Aberto
dc.subjectCompostos bioativos
dc.subjectSíntese orgânica
dc.subjectAgentes antivirais
dc.subjectAgentes antineoplásicos
dc.subjectAgentes antiinfecciosos
dc.subjectQuinoleina
dc.subjectQuímica farmacêutica
dc.subject.otherBioactive compounds
dc.subject.otherC–H activation
dc.subject.other3d metals
dc.subject.otherDrugs
dc.subject.otherMedicinal chemistry
dc.titleOn the application of 3d metals for C-H activation toward bioactive compounds: the key step for the synthesis of silver bullets
dc.typeArtigo de periódico
local.citation.epage1938
local.citation.spage1849
local.citation.volume17
local.description.resumoSeveral valuable biologically active molecules can be obtained through C–H activation processes. However, the use of expensive and not readily accessible catalysts complicates the process of pharmacological application of these compounds. A plausible way to overcome this issue is developing and using cheaper, more accessible, and equally effective catalysts. First-row transition (3d) metals have shown to be important catalysts in this matter. This review summarizes the use of 3d metal catalysts in C–H activation processes to obtain potentially (or proved) biologically active compounds.
local.identifier.orcidhttps://orcid.org/0000-0002-8515-9306
local.identifier.orcidhttps://orcid.org/0000-0003-4796-3448
local.identifier.orcidhttps://orcid.org/0000-0002-8887-2772
local.identifier.orcidhttps://orcid.org/0000-0002-8075-9716
local.identifier.orcidhttps://orcid.org/0000-0002-9882-3085
local.identifier.orcidhttps://orcid.org/0000-0003-1281-5453
local.publisher.countryBrasil
local.publisher.departmentICX - DEPARTAMENTO DE QUÍMICA
local.publisher.initialsUFMG
local.url.externahttps://www.beilstein-journals.org/bjoc/articles/17/126

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