Leishmanemia - relato de achados laboratoriais

Abstract

Leishmaniasis is considered among the major zoonotic diseases transmitted to humans and other animals by two genera of sandflies: Phlebotomus in Asia, Africa and Europe and Lutzomyia in the Americas. Amastigote forms of Leishmania were observed in blood smears of 12 animals during the observation blade for differential leukocyte counts. In 100% of CBCs anemia was observed, being the most prevalent normocytic normochromic classification (41.7%). Hyperproteinemia plasma was observed in 33% of blood counts. The main leukocyte changes were: leukocytosis (33.3%), leukopenia (33.3%), neutrophils (41.6%), neutropenia (25%), lymphopenia (75%), eosinopenia (91.7%) , monocytopenia (33.3%) and activated monocytes (33.3%). Thrombocytopenia was observed in 50% of animals. In the analysis biochemistry, the most frequent changes were: increased plasma total protein (33.3%), hypoalbuminemia (100%), hyperglobulinemia (75%), decrease of the A: G (87.5%), increased concentrations of urea and creatinine (55.5%) and the activity of ALT and ALP (33.3%), characterizing concomitant diseases. With regard to urinalysis tests, the most frequent alteration was observed proteinuria. It can be concluded that the leishmanemia is occasionally found in endemic region of canine visceral leishmaniasis (CVL) and that in such cases, anemia, thrombocytopenia and disproteinemia are common, unlike the WBC that does not show a characteristic pattern. Thus a careful evaluation of the blood smear is of paramount importance.