Longitudinal assessment of D-dimer and plasminogen activator inhibitor type-1 plasma levels in pregnant women with risk factors for preeclampsia

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dc.creatorFlavia Lucena
dc.creatorLuci Dusse
dc.creatorEura Martins Lage
dc.creatorPatricia Gonçalves Teixeira
dc.creatorAlexandre Simões Barbosa
dc.creatorRejane Diniz
dc.creatorAndre Talvani Pedrosa da Silva
dc.creatorPatricia Alpoim
dc.creatorLuisa Perucci
dc.creatorBashir Lwaleed
dc.date.accessioned2023-07-14T19:57:25Z
dc.date.accessioned2025-09-09T00:22:28Z
dc.date.available2023-07-14T19:57:25Z
dc.date.issued2019-02-13
dc.identifier.doihttps://doi.org/10.1080/10641955.2019.1577435
dc.identifier.issn10641955
dc.identifier.urihttps://hdl.handle.net/1843/56268
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofHypertension in Pregnancy
dc.rightsAcesso Restrito
dc.subjectPré-Eclâmpsia
dc.subjectEstudos Longitudinais
dc.subjectTrombofilia
dc.subject.otherPreemclampisia
dc.subject.otherD-dimer
dc.subject.otherLongitudinal Study
dc.subject.otherPai 1
dc.subject.otherHypercoagulability
dc.titleLongitudinal assessment of D-dimer and plasminogen activator inhibitor type-1 plasma levels in pregnant women with risk factors for preeclampsia
dc.typeArtigo de periódico
local.citation.epage6
local.citation.issue1
local.citation.spage1
local.citation.volume38
local.description.resumoObjective: Investigating D-Dimer/D-Di and plasminogen activator inhibitor type-1/PAI-1 levels throughout gestation in women with preeclampsia/PE risk factors.Methods: D-Di and PAI-1 plasma levels were determined in 28 women at 12–19, 20–29, 30–34 and 35–40 weeks of gestation.Results: D-Di was lower at 12–19 weeks and higher at 30–34 weeks in women who developed PE versus who did not develop it. D-Di increased throughout gestation in both groups, peaking earlier in pregnant women who developed PE versus who did not develop it. PA1-1 increased across gestation, but it didn’t differ between groups. Conclusion: D-Di was able to discriminate these groups of women at 12–19 and 30–34 weeks of gestation.
local.publisher.countryBrasil
local.publisher.departmentFAR - DEPARTAMENTO DE ANÁLISES CLÍNICAS E TOXICOLÓGICAS
local.publisher.departmentMED - DEPARTAMENTO DE GINECOLOGIA OBSTETRÍCIA
local.publisher.initialsUFMG
local.url.externahttps://www.tandfonline.com/doi/abs/10.1080/10641955.2019.1577435?journalCode=ihip20

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