Efeito de um suplemento alimentar hiperproteico à base do buriti (Mauritia flexuosa l.) na força muscular e metabolismo de camundongos submetidos a exercício resistido

Abstract

Physical inactivity, identified by the World Health Organization (WHO) as one of the major risk factors for non-communicable chronic diseases (NCDs), has worsened with the global increase in physical inactivity, negatively affecting metabolic and cardiovascular health. Physical exercise, especially resistance training, plays a fundamental role in muscle hypertrophy and metabolic improvement, enhanced by hyperproteic diets that promote protein synthesis and muscle recovery. Additionally, nutraceutical supplements, such as those derived rom Buriti (Mauritia flexuosa L.), have shown additional benefits by improving lipid profile and insulin sensitivity, contributing to the prevention and control of NCDs. The integration of regular physical exercise with a protein-rich diet and functional supplements is essential for optimizing health and physical performance. This study aimed to investigate the effects of a hyperproteic dietary supplement based on the Cerrado fruit Buriti (Mauritia flexuosa L.) associated with physical exercise (resistance training) using a ladder apparatus for mice. The experiment was conducted over 12 weeks with 32 male Swiss mice, divided into four groups (n=8): control group (AIN93M without exercise), AIN93M with exercise, AIN93M with Whey Protein and exercise, and AIN93M with Buriti-based supplement and physical exercise. Various metabolic, muscle strength, and body composition parameters were evaluated. The results indicated that the group receiving the AIN93M diet with Buriti-based supplement and physical exercise (AIN93M/B/ExF) showed significant improvements in several metabolic parameters compared to the other groups, including lower body adiposity and final body weight. The area under the body weight curve was also smaller, indicating a positive impact of the supplement and exercise on weight gain reduction. The Buriti-based supplement, when combined with physical exercise, demonstrated benefits in reducing body adiposity and glycemic control without significantly impacting muscle hypertrophy and physical strength compared to Whey Protein. The Buriti-based supplement showed promise in improving metabolic parameters, but further research is needed to better understand its effects in different contexts.