Androgen receptor in salivary gland carcinoma: a review of an old marker as a possible new target

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dc.creatorChit Cheng Yeoh
dc.creatorNedal Dabab
dc.creatorElyse Rigby
dc.creatorRitu Chhikara
dc.creatorIolia Akaev
dc.creatorRicardo Santiago Gomez
dc.creatorFelipe Paiva Fonseca
dc.creatorPeter Brennan
dc.creatorSiavash Rahimi
dc.date.accessioned2024-11-21T19:39:50Z
dc.date.accessioned2025-09-09T00:41:49Z
dc.date.available2024-11-21T19:39:50Z
dc.date.issued2018
dc.format.mimetypepdf
dc.identifier.doihttps://doi.org/10.1111/jop.12741
dc.identifier.issn1600-0714
dc.identifier.urihttps://hdl.handle.net/1843/78180
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofJournal of Oral Pathology & Medicine
dc.rightsAcesso Aberto
dc.subjectAbiraterone acetate
dc.subjectReceptors, androgen
dc.subjectImmunohistochemistry
dc.subjectCarcinoma, mucoepidermoid
dc.subjectCarcinoma, adenoid cystic
dc.subjectAdenocarcinoma
dc.subjectPrognosis
dc.subjectRadiotherapy
dc.subjectExcision repair
dc.subjectAndrogen antagonists
dc.subjectDrug therapy
dc.subject.otherAbiraterone
dc.subject.otherandrogen receptor
dc.subject.otherEnzalutamide
dc.subject.otherHead and neck
dc.subject.otherimmunohistochemistry
dc.subject.otherNon-squamous cell carcinoma
dc.subject.otherSalivary gland carcinoma
dc.titleAndrogen receptor in salivary gland carcinoma: a review of an old marker as a possible new target
dc.typeArtigo de periódico
local.citation.epage695
local.citation.issue7
local.citation.spage691
local.citation.volume47
local.description.resumoThe role of the androgen receptor (AR) as an immunomarker for diagnosis of salivary gland duct carcinoma (SDC) is well known. Other non-squamous cell head and neck cancers (NSCC-HN), including a small subset of salivary gland cancers (SGCs), can also express AR. With the increase in effective and powerful new generation of anti-androgen agents and drugs administered orally, more targetable AR-driven NSCC-HN, such as subsets of SGCs, should be investigated for possible expression of AR. In this review, we focus on SGC subtypes, which could express AR and describe the main androgen deprivation therapy (ADT) strategies.
local.identifier.orcidhttps://orcid.org/0000-0001-6026-9843
local.identifier.orcidhttps://orcid.org/0000-0001-9214-9301
local.identifier.orcidhttps://orcid.org/0000-0002-4351-8147
local.identifier.orcidhttps://orcid.org/0000-0001-8770-8009
local.identifier.orcidhttps://orcid.org/0000-0002-6657-4547
local.identifier.orcidhttps://orcid.org/0000-0003-4804-3264
local.identifier.orcidhttps://orcid.org/0000-0002-8282-1480
local.publisher.countryBrasil
local.publisher.departmentFAO - DEPARTAMENTO DE CLÍNICA
local.publisher.initialsUFMG
local.url.externahttps://onlinelibrary.wiley.com/doi/10.1111/jop.12741

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