Synthesis of 25X-BOMes and 25X-NBOHs (X = H, I, Br) for pharmacological studies and as reference standards for forensic purposes
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Universidade Federal de Minas Gerais
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Artigo de periódico
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Membros da banca
Resumo
An expeditious method is reported for the synthesis of three NBOHs (25H-, 25I- and 25B-NBOH; 9–38% overall yield) and three NBOMes (25H-, 25I- and 25B-NBOMe; 7–33% overall yield) from salicylaldehyde and 2-methoxyaldehyde, respectively. The X-ray structures of 25H-, 25I- and 25B-NBOH.HCl were also determined. Our approach should provide a general entry for preparing such a class of substances for pharmacological and forensic purposes.
Abstract
Assunto
Química legal, Fenetilamina, Psicotrópicos, Cromatografia de gás - Aplicações Forenses, Aminas, Aldeídos
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Phenethylamines, Reference standards, NBOMes, NBOHs
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https://www.sciencedirect.com/science/article/pii/S0040403920313289