Infection surveillance in pediatric hematopoietic stem cell transplantation recipients

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dc.creatorDaniela Caldasteixeira
dc.creatorLilian Martins Oliveira Diniz
dc.creatorPaulo Henrique Orlandi Mourão
dc.creatorFabiana Maria Kakehasi
dc.creatorAntonio Vaz de Macedo
dc.creatorHelena Duani
dc.creatorWanessa Trindade Clemente
dc.creatorKarla Emília de sá Rodrigues
dc.creatorRoberta Maia de Castro Romanelli
dc.date.accessioned2023-07-03T20:21:07Z
dc.date.accessioned2025-09-08T23:28:12Z
dc.date.available2023-07-03T20:21:07Z
dc.date.issued2017
dc.format.mimetypepdf
dc.identifier.doi10.1111/ejh.12982
dc.identifier.issn09024441
dc.identifier.urihttps://hdl.handle.net/1843/55700
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofEuropean Journal of Haematology
dc.rightsAcesso Restrito
dc.subjectTransplante de Medula Óssea
dc.subjectHematologia
dc.subjectTransplante de Células-Tronco Hematopoéticas
dc.subject.otherbone marrow transplantation
dc.subject.otherHematology
dc.subject.otherImmunology and infectious diseases
dc.subject.otherHematopoietic stem cell transplantation
dc.titleInfection surveillance in pediatric hematopoietic stem cell transplantation recipients
dc.typeArtigo de periódico
local.citation.epage74
local.citation.issue100
local.citation.spage69
local.description.resumoObjective: To describe the profile of reported healthcare- associated infections (HAIs) in pediatric patients submitted to hematopoietic stem cell transplantation (HSCT) at a reference center.Methods: Retrospective cohort of pediatric patients who were submitted to HSCT from 2008 to 2016. The criteria for HAI were based on those established by the National Healthcare Safety Network. Data were collected by active surveillance per formed daily by professionals. This study was approved by the institutional research ethics committee. Results: A total of 86 HSCTs were performed in 81 patients younger than 18 years of age (median, 10 years). Of these, 69 (85%) were males. Aplastic anemia and leukemia were the main diagnoses. A total of 140 HAIs were diagnosed with an incidence density of 28.2 infections/1000 patient- days. The most common HAI was laboratory confirmed bloodstream infection (46), the majority of which was reported to be central venous catheter- associated (43). Gram- negative bacteria were the most prevalent mi croorganisms (58.5%). Almost all the infections occurred until 30 days after transplan tation, and 17 deaths were observed within 180 days after the procedure. Conclusion: Active surveillance of HAIs in HSCT children allowed the evaluation of the incidence and profile of HAIs, which is essential for the health care of these patients.
local.identifier.orcidhttps://orcid.org/0000-0003-0848-3740
local.publisher.countryBrasil
local.publisher.departmentMED - DEPARTAMENTO DE CLÍNICA MÉDICA
local.publisher.departmentMED - DEPARTAMENTO DE PEDIATRIA
local.publisher.initialsUFMG
local.url.externahttps://onlinelibrary.wiley.com/doi/10.1111/ejh.12982

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